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Rhodopsin peptide

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50ug
- +
产品详情
  • 产品名称

    Rhodopsin多肽
    参阅全部 Rhodopsin 蛋白酶

  • 纯度

    > 70 % HPLC.
    Peptides are analyzed by Reverse-Phase HPLC (RP-HPLC) in order to determine purity. Identities are confirmed by MALDI-MS.

  • 无动物成分

    No

  • 性质

    Synthetic

  • 应用

    Blocking

  • 形式

    Lyophilized

  • 补充说明


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and bovine rhodopsin, catalog ab3424. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • 复溶

    >95% pure, lyophilized synthetic peptide. Reconstitute with 0.1 ml of distilled water.

别名

  • CSNBAD1

  • MGC138309

  • MGC138311

  • OPN 2

  • OPN2

  • opsd

  • OPSD_HUMAN

  • opsin 2

  • Opsin 2 rod pigment

  • Opsin-2

  • Opsin2

  • Retinitis Pigmentosa 4

  • Retinitis pigmentosa 4 autosomal dominant

  • RHO

  • Rhodopsin

  • RP 4

  • RP4

  • 功能

    Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.

  • 组织特异性

    Rod shaped photoreceptor cells which mediates vision in dim light.

  • 疾病相关

    Retinitis pigmentosa 4
    Night blindness, congenital stationary, autosomal dominant 1

  • 序列相似性

    Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.

  • 翻译后修饰

    Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
    Contains one covalently linked retinal chromophore.

  • 细胞定位

    Membrane. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia.