| 存储条件 |
|---|
| Product Name | PTBP1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 57 kDa RNA binding protein PPTB 1 antibody 57 kDa RNA-binding protein PPTB-1 antibody Heterogeneous nuclear ribonucleoprotein I antibody Heterogeneous Nuclear Ribonucleoprotein Polypeptide I antibody hnRNP I antibody HNRNP-I antibody HNRNPI antibody HNRPI antibody MGC10830 antibody MGC8461 antibody Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) antibody Polypyrimidine Tract Binding Protein 1 antibody Polypyrimidine tract binding protein antibody Polypyrimidine tract-binding protein 1 antibody pPTB antibody PTB 1 antibody PTB 2 antibody PTB 3 antibody PTB 4 antibody PTB antibody PTB T antibody PTB1 antibody PTB2 antibody PTB3 antibody PTB4 antibody PTBP 1 antibody PTBP1 antibody PTBP1_HUMAN antibody PTBT antibody RNA Binding Protein antibody |
| Product description | Polypyrimidine tract-binding protein 1 is a protein that in humans is encoded by the PTBP1 gene. It plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. PTBP1 activates exon skipping of its own pre-mRNA during muscle cell differentiation. It binds to the polypyrimidine tract of introns and may promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. PTBP1 may promote the binding of U2 snRNP to pre-mRNA. It cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHC |
| WB:1:1000-1:2000 IHC:1:200 ICC:1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | 57 kDa RNA binding protein PPTB 1 antibody 57 kDa RNA-binding protein PPTB-1 antibody Heterogeneous nuclear ribonucleoprotein I antibody Heterogeneous Nuclear Ribonucleoprotein Polypeptide I antibody hnRNP I antibody HNRNP-I antibody HNRNPI antibody HNRPI antibody MGC10830 antibody MGC8461 antibody Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) antibody Polypyrimidine Tract Binding Protein 1 antibody Polypyrimidine tract binding protein antibody Polypyrimidine tract-binding protein 1 antibody pPTB antibody PTB 1 antibody PTB 2 antibody PTB 3 antibody PTB 4 antibody PTB antibody PTB T antibody PTB1 antibody PTB2 antibody PTB3 antibody PTB4 antibody PTBP 1 antibody PTBP1 antibody PTBP1_HUMAN antibody PTBT antibody RNA Binding Protein antibody |
|---|---|
| Molecular Weight(MW) | 57 kDa |
| Cellular Localization | Nucleus |
| SwissProt ID | P26599 |
|---|
Application
Fig1: Western blot analysis on cell lysates using anti- PTBP1 rabbit polyclonal antibodies.
Application
Fig2: ICC staining PTBP1 in Hela cells (green). Cells were fixed in paraformaldehyde.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti- PTBP1 rabbit polyclonal antibody.| Positive Control | Jurkat, Daudi, A549, rat heart, PC12, NIH/3T3, F9, Hela , mouse testis |
|---|---|
| Application Notes | WB:1:1000-1:2000 IHC:1:200 ICC:1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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