Gamma-ring complex protein 104 kDa antibody Gamma-tubulin complex component 3 antibody GCP-3 antibody GCP3 antibody GCP3_HUMAN antibody h104p antibody hGCP3 antibody hGrip104 antibody hSpc98 antibody SPBC98 antibody Spc98p antibody Spindle pole body protein Spc98 homolog antibody TUBGCP3 antibody Tubulin gamma complex associated protein 3 antibody
Product description
γ-Tubulin, another member of the tubulin family, is important in the nucleation and polar orientation of microtubules. It is found primarily in centrosomes and spindle pole bodies, since these are the areas of most abundant microtubule nucleation. In these organelles, several γ-tubulin and other protein molecules are found in complexes known as γ-tubulin ring complexes (γ-TuRCs), which chemically mimic the (+) end of a microtubule and thus allow microtubules to bind. γ-tubulin also has been isolated as a dimer and as a part of a γ-tubulin small complex (γTuSC), intermediate in size between the dimer and the γTuRC. Phosphorylation at Ser-131 by BRSK1 regulates centrosome duplication, possibly by mediating relocation of gamma-tubulin and its associated proteins from the cytoplasm to the centrosome.
Immunogen
peptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBICCIHC
WB:1:1,000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
Gamma-ring complex protein 104 kDa antibody Gamma-tubulin complex component 3 antibody GCP-3 antibody GCP3 antibody GCP3_HUMAN antibody h104p antibody hGCP3 antibody hGrip104 antibody hSpc98 antibody SPBC98 antibody Spc98p antibody Spindle pole body protein Spc98 homolog antibody TUBGCP3 antibody Tubulin gamma complex associated protein 3 antibody