Anti-IL-21抗体
参阅全部 IL-21 一抗
兔多克隆抗体to IL-21
Rabbit
适用于: IHC-P, ICC/IF, WBmore details
与反应: Mouse, Rat, Human
预测可用于: Cow, Dog, Pig
Synthetic peptide corresponding to Human IL-21 aa 121-135.
Sequence:
TCPSCDSYEKKPPKE
A novel cytokine was recently identified in human and mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
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Liquid
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
pH: 7.2
Preservative: 0.02% Sodium azide
Immunogen affinity purified
A novel cytokine was recently identified in human and mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
多克隆
IgG
Abpromise™承诺保证使用ab5978于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P | (1) | Use a concentration of 0.5 - 2 µg/ml. |
| ICC/IF | Use a concentration of 2 µg/ml. | |
| WB | (1) | Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 18 kDa. |
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Unigene: 157689 Mouse
Unigene: 214949 Rat
Entrez Gene: 59067 Human
Entrez Gene: 60505 Mouse
Omim: 605384 Human
SwissProt: Q9HBE4 Human
SwissProt: Q9ES17 Mouse
Unigene: 567559 Human
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Western blot - Anti-IL-21 antibody (ab5978)
Anti-IL-21 antibody (ab5978) at 1 µg/ml + Recombinant human IL-21 protein (ab73250) at 0.1 µg
Secondary
Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Exposure time: 8 minutes
Immunocytochemistry/ Immunofluorescence - Anti-IL-21 antibody (ab5978)
ab5978 at 2ug/ml staining of IL21 in K562 cells.
