Anti-CYP2A6 antibody

• 产品名称

  Anti-CYP2A6抗体
  参阅全部 CYP2A6 一抗

• 描述

  兔多克隆抗体to CYP2A6

• 宿主

  Rabbit

• 经测试应用

  适用于: WBmore details

• 种属反应性

  与反应: Human
  

• 免疫原

  Recombinant full length protein (His-tag) corresponding to Human CYP2A6. Purified, His-tagged, full length human P450 2A6 fusion protein.

• 阳性对照

• WB: HepG2 cells.

• 常规说明

  
  

  The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

  If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

• 形式

  Liquid

• 存放说明

  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

• 存储溶液

  Preservative: 0.05% Sodium azide
  Constituent: 99% PBS

• 纯度

  IgG fraction

• Primary antibody说明

  The Cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.

• 克隆

  多克隆

• 同种型

  IgG

The Abpromise guarantee

Abpromise™承诺保证使用ab3570于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

• 数据库链接

• Entrez Gene: 1548 Human

• Omim: 122720 Human

• SwissProt: P11509 Human

• Unigene: 250615 Human

• 别名

• CPA6 antibody

• CYP2A antibody

• CYP2A3 antibody

• CYP2A6 antibody

• CYPIIA6 antibody

• Cytochrome P450 2A6 antibody

• Cytochrome P450 IIA3 antibody

• Cytochrome P450 subfamily IIA (phenobarbital inducible) polypeptide 6 antibody

• Cytochrome P450(I) antibody

• Cytochrome P450, family 2 subfamily A polypeptide 6 antibody

• Flavoprotein linked monooxygenase antibody

• P450C2A antibody

• P450PB antibody

• Xenobiotic monooxygenase antibody

• Coumarin 7 hydroxylase antibody

• Coumarin 7-hydroxylase antibody

• CP2A6_HUMAN antibody

• 

  Western blot - Anti-CYP2A6 antibody (ab3570)

  All lanes : Anti-CYP2A6 antibody (ab3570) at 1/1000 dilution
  
  Lane 1 : Hep G2 whole cell extract
  Lane 2 : Mouse Pancreas whole cell extract
  
  Lysates/proteins at 30 µg per lane.
  
  Secondary
  All lanes : Goat anti-Rabbit IgG (H+L) HRP conjugate at 1/5000 dilution
  
  Predicted band size: 57 kDa
  
  
  
  

  A 56 kDa band corresponding to Cytochrome P450 2A6 was observed in Hep G2 but not in Mouse Pancreas.

  Blocking buffer: 5 % skimmed milk.