Anti-AANAT antibody

• 产品名称

  Anti-AANAT抗体
  参阅全部 AANAT 一抗

• 描述

  兔多克隆抗体to AANAT

• 宿主

  Rabbit

• 经测试应用

  适用于: WBmore details

• 种属反应性

  与反应: Human
  预测可用于: Mouse, Hamster, Chimpanzee, Rhesus monkey

• 免疫原

  Synthetic peptide corresponding to Rat AANAT aa 150 to the C-terminus (C terminal).
  Database link: Q64666
  (Peptide available as ab5004)

  Run BLAST with Run BLAST with 

• 常规说明

  
  

  The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

  If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

• 形式

  Liquid

• 存放说明

  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

• 存储溶液

  Preservative: 0.05% Sodium azide
  Constituents: 0.1% BSA, 99% PBS

• 浓度

• 50 µg 浓度为 1 mg/ml

• 纯度

  Immunogen affinity purified

• 纯化说明

  Total anti-C-terminal AA-NAT-specific IgG was affinity purified on resin-coupled non-phosphopeptide. Phospho-specific carboxy-terminal IgG was subsequently isolated on resin-coupled phosphopeptide.

• Primary antibody说明

  Pineal gland serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AA-NAT) is an ~23 kDa protein which is the rate-limiting enzyme in melatonin synthesis. Melatonin serves as the hormonal signal of the daily light/dark cycle, or body clock. The nocturnal oscillation in enzyme activity ranges by 10- to 100-fold depending on species among vertebrates. Studies have shown that AA-NAT is regulated by cAMP at both the mRNA and protein levels. AA-NAT has putative protein kinase A (PKA) sites at Thr29 and Ser206. Phosphorylation of AA-NAT at these residues might play a role in protein inactivation via proteasome-dependent degradation.

• 克隆

  多克隆

• 同种型

  IgG

The Abpromise guarantee

Abpromise™承诺保证使用ab3506于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

数据库链接

• Entrez Gene: 503504 Chimpanzee

• Entrez Gene: 15 Human

• Entrez Gene: 11298 Mouse

• Omim: 600950 Human

• SwissProt: Q5IS55 Chimpanzee

• SwissProt: Q16613 Human

• SwissProt: O88816 Mouse

• Unigene: 431417 Human

• Unigene: 418559 Mouse

• Unigene: 42233 Mouse

别名

• AA-NAT antibody

• Aanat antibody

• Aralkylamine N-acetyltransferase antibody

• Arylalkylamine N acetyltransferase antibody

• Serotonin acetylase antibody

• Serotonin N-acetyltransferase antibody

• SNAT antibody

• SNAT_HUMAN antibody

• 

  Western blot - Anti-AANAT antibody (ab3506)

  Western blot of Serotonin N-acetyltransferase in transfected 293T cell lysate using ab3506.