| 存储条件 |
|---|
| Product Name | CIRBP [B3-E12] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | A18 hnRNP antibody A18HNRNP antibody cirbp antibody CIRBP_HUMAN antibody CIRP antibody Cold inducible RNA binding protein antibody Cold-inducible RNA-binding protein antibody Glycine rich RNA binding protein antibody Glycine-rich RNA-binding protein CIRP antibody testicular tissue protein Li 39 antibody |
| Product description | Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500-1:1,000 IHC:1:50-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | A18 hnRNP antibody A18HNRNP antibody cirbp antibody CIRBP_HUMAN antibody CIRP antibody Cold inducible RNA binding protein antibody Cold-inducible RNA-binding protein antibody Glycine rich RNA binding protein antibody Glycine-rich RNA-binding protein CIRP antibody testicular tissue protein Li 39 antibody |
|---|---|
| Molecular Weight(MW) | 19 kDa |
| Cellular Localization | Nucleus. Cytoplasm. |
| SwissProt ID | Q14011 |
|---|
Application
Fig1: Western blot analysis of CIRBP on human CIRBP recombinant protein using anti-CIRBP antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of CIRBP on HEK293 (1) and CIRBP-hIgGFc transfected HEK293 (2) cell lysate using anti-CIRBP antibody at 1/1,000 dilution.
Application
Fig3: Western blot analysis of CIRBP on different cell lysate using anti-CIRBP antibody at 1/1,000 dilution. Positive control： Line1: SW480 Line2: PC-3 Line3: A431 Line4: U251
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human bladder cancer tissue using anti-CIRBP antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human rectum cancer tissue using anti-CIRBP antibody. Counter stained with hematoxylin.| Positive Control | Human CIRBP recombinant protein, CIRBP-hIgGFc transfected HEK293 cell lysate, SW480, PC-3, A431, U251 cell lysate, human bladder cancer tissue, human rectum cancer tissue. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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