Anti-GDNF Receptor alpha 2/GFRA2抗体
参阅全部 GDNF Receptor alpha 2/GFRA2 一抗
兔多克隆抗体to GDNF Receptor alpha 2/GFRA2
Rabbit
适用于: ICC/IF, WBmore details
与反应: Human
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
Members of the glial cell line-derived neurotrophic factor(GDNF) family, including GDNF and neurturin (NTN),play key roles in the control of vertebrate neuron survivaland differentiation. Physiological responses to NTN requirethe presence of a novel glycosylphosphadidylinositollinked protein NTNRa, which is a cell surface receptor forNTN. The cDNAs encoding NTNRa from human, rat,chicken, and mouse have been cloned recently. NTNRa was also termed GDNFRb, Ret ligand 2 (RETL2)or TGF-b-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRa-2 recently. GFRa-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRa-2, and the Ret PTK form a complex to transduce NTN signal andto mediate NTN function.
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Liquid
Shipped at 4°C. Store at +4°C.
pH: 7.2
Preservative: 0.02% Sodium azide
浓度
100 µg 浓度为 1 mg/ml
Ion Exchange Chromatography
Members of the glial cell line-derived neurotrophic factor(GDNF) family, including GDNF and neurturin (NTN),play key roles in the control of vertebrate neuron survivaland differentiation. Physiological responses to NTN requirethe presence of a novel glycosylphosphadidylinositollinked protein NTNRa, which is a cell surface receptor forNTN. The cDNAs encoding NTNRa from human, rat,chicken, and mouse have been cloned recently. NTNRa was also termed GDNFRb, Ret ligand 2 (RETL2)or TGF-b-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRa-2 recently. GFRa-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRa-2, and the Ret PTK form a complex to transduce NTN signal andto mediate NTN function.
多克隆
IgG
Abpromise™承诺保证使用ab8027于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC/IF | Use a concentration of 5 µg/ml. | |
| WB | Use at an assay dependent concentration. |
Entrez Gene: 2675 Human
Omim: 601956 Human
SwissProt: O00451 Human
Unigene: 441202 Human
GDNF receptor beta antibody
GDNFR beta antibody
GDNFR-alpha-2 antibody
GDNFR-beta antibody
GDNFRB antibody
GFR alpha 2 antibody
GFR-alpha-2 antibody
GFRA 2 antibody
Gfra2 antibody
GFRA2_HUMAN antibody
Glial cell line derived neurotrophic factor family receptor alpha2b antibody
Glial cell line derived neurotrophic factor receptor beta antibody
Neurturin receptor alpha antibody
NRTNR alpha antibody
NRTNR-alpha antibody
NTNR alpha antibody
NTNR-alpha antibody
NTNRA antibody
PI linked cell surface accessory protein antibody
PI linked cell-surface accessory protein antibody
RET ligand 2 antibody
RETL 2 antibody
RETL2 antibody
TGF beta related neurotrophic factor receptor 2 antibody
TGF-beta-related neurotrophic factor receptor 2 antibody
TRN receptor GPI anchored antibody
TRNR 2 antibody
TRNR2 antibody
GDNF family receptor alpha 2 antibody
GDNF family receptor alpha-2 antibody
GDNF receptor alpha-2 antibody
Western blot - Anti-GDNF Receptor alpha 2/GFRA2 antibody (ab8027)
Anti-GDNF Receptor alpha 2/GFRA2 antibody (ab8027) at 1/1000 dilution + HeLa total cell lysate
Observed band size: 52 kDawhy is the actual band size different from the predicted?
Immunocytochemistry/ Immunofluorescence - Anti-GDNF Receptor alpha 2/GFRA2 antibody (ab8027)
ab8027 at 5µg/ml staining GDNF Receptor alpha2/GFRA2 in Hela cells by ICC/IF.
