| 存储条件 |
|---|
| Product Name | FUT4 [B4-B11] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 3)-fucosyltransferase antibody Alpha-(1 antibody Alpha-(1,3)-fucosyltransferase antibody Alpha-3-fucosyltransferase antibody ELAM-1 ligand fucosyltransferase antibody ELFT antibody FCT3A antibody Fuc-TIV antibody Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific antibody Fucosyltransferase 4 antibody Fucosyltransferase IV antibody FucT-IV antibody Fut4 antibody FUT4_HUMAN antibody FUTIV antibody Galactoside 3-L-fucosyltransferase antibody Lewis X antibody LeX antibody SSEA-1 antibody Stage-Specific Embryonic Antigen 1 antibody |
| Product description | Fucosyltransferases (FucTs) catalyze the covalent association of fucose to different positional linkages on sugar acceptor molecules. The carbohydrate moieties that are generated are covalently attached to cell surfaces and are necessary to ensure a surface contour that satisfies a variety of physiological roles. CD15, also known as Lewis X or LeX, is a carbohydrate antigen that is generated by FucT-IV (alpha 1,3-fucosyltransferase IV). Commonly found on the surface of leukocytes and some tumor cells, CD15 is a trisaccharide that is synthesized when FucT-IV transfers an α-fucose residue onto the β-GlcNAc moiety of cellular N-acetyllactosamines. CD15 functions as an adhesion molecule capable of calcium-mediated homotypic binding. Cells with high surface expression of CD15, therefore, exhibit strong self-aggregation (based on CD15-CD15 interaction) in the presence of calcium. Additionally, CD15 is thought to be a ligand for Selectins (proteins involved in mediating leukocyte-specific cellular interactions), further supporting its role as a cell-adhesion protein. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500-1:2,000 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | 3)-fucosyltransferase antibody Alpha-(1 antibody Alpha-(1 3)-fucosyltransferase antibody Alpha-3-fucosyltransferase antibody ELAM-1 ligand fucosyltransferase antibody ELFT antibody FCT3A antibody Fuc-TIV antibody Fucosyltransferase 4 (Alpha (1 3) Fucosyltransferase Myeloid-Specific antibody Fucosyltransferase 4 antibody Fucosyltransferase IV antibody FucT-IV antibody Fut4 antibody FUT4_HUMAN antibody FUTIV antibody Galactoside 3-L-fucosyltransferase antibody Lewis X antibody LeX antibody SSEA-1 antibody Stage-Specific Embryonic Antigen 1 antibody |
|---|---|
| Molecular Weight(MW) | 59 kDa |
| Cellular Localization | Golgi Apparatus, membrane-bound form in trans cisternae of Golgi. |
| SwissProt ID | P22083 |
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Application
Fig1: Western blot analysis of FUT4 on human FUT4 recombinant protein using anti-FUT4 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of FUT4 on HEK293 (1) and FUT4-hIgGFc transfected HEK293 (2) cell lysate using anti-FUT4 antibody at 1/1,000 dilution.
Application
Fig3: Western blot analysis of FUT4 on Jurkat cell lysate using anti-FUT4 antibody at 1/1,000 dilution.| Positive Control | Human FUT4 recombinant protein, FUT4-hIgGFc transfected HEK293 cell lysate, Jurkat cell lysate, |
|---|---|
| Application Notes | WB:1:500-1:2,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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