| 存储条件 |
|---|
| Product Name | IGFBP7 [E7-D9] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AGM antibody Angiomodulin antibody FSTL2 antibody IBP-7 antibody IBP7 antibody IBP7_HUMAN antibody IGF binding protein 7 antibody IGF-binding protein 7 antibody IGFBP rP1 antibody IGFBP-7 antibody IGFBP-rP1 antibody IGFBP7 antibody IGFBPRP1 antibody Insulin like growth factor binding protein 7 antibody Insulin-like growth factor-binding protein 7 antibody MAC25 antibody MAC25 protein antibody PGI2 stimulating factor antibody PGI2-stimulating factor antibody Prostacyclin stimulating factor antibody Prostacyclin-stimulating factor antibody PSF antibody RAMSVPS antibody TAF antibody Tumor-derived adhesion factor antibody |
| Product description | The Insulin-like growth factor-binding proteins (IGFBPs) are a family of homologous proteins that have co-evolved with the IGFs. They serve not only as shuttle molecules for the soluble IGFs, but also confer a level of regulation to the IGF signaling system. Physical association of the IGFBPs with IGF influences the bio-availability of the growth factors, as well as their concentration and distribution in the extracellular environment. In addition, the IGFBPs appear to have biological activity independent of the IGFs. Seven IGFBPs have been described, each differing in their tissue distribution, half-lives and modulation of IGF interactions with their receptors. IGFBP-7 is a secreted protein that binds both IGF-I and IGF-II with a relatively low affinity. It stimulates pros-tacyclin production and may also function as a growth-suppressing factor. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500-1:2,000 IHC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | AGM antibody Angiomodulin antibody FSTL2 antibody IBP-7 antibody IBP7 antibody IBP7_HUMAN antibody IGF binding protein 7 antibody IGF-binding protein 7 antibody IGFBP rP1 antibody IGFBP-7 antibody IGFBP-rP1 antibody IGFBP7 antibody IGFBPRP1 antibody Insulin like growth factor binding protein 7 antibody Insulin-like growth factor-binding protein 7 antibody MAC25 antibody MAC25 protein antibody PGI2 stimulating factor antibody PGI2-stimulating factor antibody Prostacyclin stimulating factor antibody Prostacyclin-stimulating factor antibody PSF antibody RAMSVPS antibody TAF antibody Tumor-derived adhesion factor antibody |
|---|---|
| Molecular Weight(MW) | 29 kDa |
| Cellular Localization | Secreted. |
| SwissProt ID | Q16270 |
|---|
Application
Fig1: Western blot analysis of IGFBP7 on human IGFBP7 recombinant protein using anti-IGFBP7 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of IGFBP7 on HEK293 (1) and IGFBP7-hIgGFc transfected HEK293 (2) cell lysate using anti-IGFBP7 antibody at 1/1,000 dilution.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti-IGFBP7 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue using anti-IGFBP7 antibody. Counter stained with hematoxylin.| Positive Control | Human IGFBP7 recombinant protein, IGFBP7-hIgGFc transfected HEK293 cell lysate, human ovarian cancer tissue, human cervical cancer tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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