| 存储条件 |
|---|
| Product Name | CAV2 [2E-9E] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CAV antibody CAV2 antibody CAV2_HUMAN antibody Caveolae protein 20 kD antibody Caveolin 2 antibody Caveolin 2 isoform a and b antibody Caveolin-2 antibody MGC12294 antibody OTTHUMP00000025032 antibody OTTHUMP00000195982 antibody |
| Product description | Caveolae (also known as plasmalemmal vesicles) are 50-100 nM flask-shaped membranes that represent a subcompartment of the plasma membrane. On the basis of morphological studies, caveolae have been implicated to function in the transcytosis of various macromolecules (including LDL) across capillary endothelial cells, uptake of small molecules via potocytosis and the compartmentalization of certain signaling molecules including G protein-coupled receptors. Three proteins, caveolin-1, caveolin-2 and caveolin-3, have been identified as principal components of caveolae (6-8). Two forms of caveolin-1, designated alpha and beta, share a distinct but overlapping cellular distribution and differ by an amino terminal 31 amino acid sequence which is absent from the beta isoform. Caveolin-1 shares 31% identity with caveolin-2 and 65% identity with caveolin-3 at the amino acid level. Functionally, the three proteins differ in their interactions with heterotrimeric G protein isoforms (6-8) |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Host Species | Mouse |
| Tested Applications | WBIHCFC |
| WB:1:500-1:2,000 IHC:1:50-1:200 FC:1:50-1:100 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | CAV antibody CAV2 antibody CAV2_HUMAN antibody Caveolae protein 20 kD antibody Caveolin 2 antibody Caveolin 2 isoform a and b antibody Caveolin-2 antibody MGC12294 antibody OTTHUMP00000025032 antibody OTTHUMP00000195982 antibody |
|---|---|
| Molecular Weight(MW) | 18 kDa |
| Cellular Localization | Nucleus. Cytoplasm. Golgi apparatus membrane. Cell membrane. |
| SwissProt ID | P51636 |
|---|
Application
Fig1: Western blot analysis of caveolin-2 on human caveolin-2 recombinant protein using anti- caveolin-2 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of caveolin-2 on HEK293 (1) and caveolin-2-hIgGFc transfected HEK293 (2) cell lysate using anti- caveolin-2
Application
Fig3: Western blot analysis of caveolin-2 on different cell lysate using anti- caveolin-2 antibody at 1/1,000 dilution. Positive control： Line1: A549 Line2: 3T3-L1 Line3: A431
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissue using anti- caveolin-2 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissue using anti- caveolin-2 antibody. Counter stained with hematoxylin.
Application
Fig6: Flow cytometric analysis of A549 cells with caveolin-2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human caveolin-2 recombinant protein, caveolin-2-hIgGFc transfected HEK293 cell lysate, A549, 3T3-L1, A431, human endometrial cancer tissue, human esophageal cancer tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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