| 存储条件 |
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| Product Name | EZH2 [6F-4G] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Enhancer of zeste 2 antibody enhancer of zeste 2 polycomb repressive complex 2 subunit antibody Enhancer of zeste homolog 2 (Drosophila) antibody Enhancer of zeste homolog 2 antibody Enhancer of zeste, Drosophila, homolog 2 antibody ENX 1 antibody Enx 1h antibody ENX-1 antibody ENX1 antibody Enx1h antibody EZH 2 antibody EZH1 antibody EZH2 antibody EZH2_HUMAN antibody EZH2b antibody Histone-lysine N-methyltransferase EZH2 antibody KMT 6 antibody KMT6 antibody KMT6A antibody Lysine N-methyltransferase 6 antibody MGC9169 antibody WVS antibody WVS2 antibody |
| Product description | In Drosophila, the Polycomb (PcG) gene family encodes chromatin proteins that are required for the repression of homeotic loci in embryonic development. PcG proteins work in conjunction with the trithorax-group (trxG), which activate homeobox gene expression during embryonic development. ENX-1, a mammalian homolog of the Drosophila gene enhancer of zeste, is a PcG protein that is ubiquitously expressed during early embryogenesis and becomes restricted to the central and peripheral nervous systems and sites of fetal hematopoiesis during later development. In the adult, ENX-1 is restricted to specific sites, including spleen, testis and placenta. The gene encoding human ENX-1 transcribes a 746 amino acid polypeptide which contains a trithorax-like domain and a DNA-binding motif. ENX-1 interacts with the proto-oncogene product Vav and is thought to be involved in the proliferation of normal and malignant hematopoietic cells. By altering the regulation of target genes, ENX-1 may also contribute to certain phenotypes of Down syndrome. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIHCFC |
| WB:1:500-1:2,000 IHC:1:200-1:500 FC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | Enhancer of zeste 2 antibody enhancer of zeste 2 polycomb repressive complex 2 subunit antibody Enhancer of zeste homolog 2 (Drosophila) antibody Enhancer of zeste homolog 2 antibody Enhancer of zeste Drosophila homolog 2 antibody ENX 1 antibody Enx 1h antibody ENX-1 antibody ENX1 antibody Enx1h antibody EZH 2 antibody EZH1 antibody EZH2 antibody EZH2_HUMAN antibody EZH2b antibody Histone-lysine N-methyltransferase EZH2 antibody KMT 6 antibody KMT6 antibody KMT6A antibody Lysine N-methyltransferase 6 antibody MGC9169 antibody WVS antibody WVS2 antibody |
|---|---|
| Molecular Weight(MW) | 86 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | Q15910 |
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Application
Fig1: Western blot analysis of EZH2 on human EZH2 recombinant protein using anti-EZH2 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of EZH2 on HEK293 (1) and EZH2-hIgGFc transfected HEK293 (2) cell lysate using anti-EZH2 antibody at 1/1,000 dilution.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-EZH2 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-EZH2 antibody. Counter stained with hematoxylin.
Application
Fig5: Flow cytometric analysis of Hela cells with EZH2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human EZH2 recombinant protein, EZH2-hIgGFc transfected HEK293 cell lysate, human lung cancer tissue, human colon cancer tissue, Hela. |
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| Application Notes | WB:1:500-1:2,000 IHC:1:200-1:500 FC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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