| 存储条件 |
|---|
| Product Name | CTHRC1 [5H1] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Collagen triple helix repeat containing 1 antibody Collagen triple helix repeat containing protein 1 antibody Collagen triple helix repeat-containing protein 1 antibody CTHR1_HUMAN antibody Cthrc1 antibody NMTC1 protein antibody Protein NMTC1 antibody |
| Product description | CTHRC1 (collagen triple helix repeat containing 1) is a 243 amino acid secreted protein that localizes to the extracellular matrix and contains one collagen-like domain. Expressed as two alternatively spliced isoforms, the first of which is expressed in calcified atherosclerotic plaque and chondrocyte-like cells, CTHRC1 is thought to function as a negative regulator of collagen matrix deposition and may also play a role in the stabilization of ligand-receptor interactions in the Wnt pathway. CTHRC1 is widely present in a variety of cancers, including melanoma and breast carcinoma, and may participate in cancer cell migration and cancer tissue invasion and metastasis. The gene encoding CTHRC1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500-1:1,000 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | Collagen triple helix repeat containing 1 antibody Collagen triple helix repeat containing protein 1 antibody Collagen triple helix repeat-containing protein 1 antibody CTHR1_HUMAN antibody Cthrc1 antibody NMTC1 protein antibody Protein NMTC1 antibody |
|---|---|
| Molecular Weight(MW) | 26 kDa |
| Cellular Localization | Extracellular matrix. Secreted. |
Application
Fig1: Western blot analysis of CTHRC1 on CTHRC1 recombinant protein using anti-CTHRC1 antibody at 1/500 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CTHRC1 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-CTHRC1 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded rat large intestine tissue using anti-CTHRC1 antibody. Counter stained with hematoxylin.| Positive Control | CTHRC1 recombinant protein, rat large intestine tissue, human kidney tissue, human placenta tissue. |
|---|---|
| Application Notes | WB:1:500-1:1,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
抱歉，暂无相关文献
