| 存储条件 |
|---|
| Product Name | MTERFD1 [A8-A10] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CGI 12 antibody mitochondrial antibody Mitochondrial transcription termination factor 3 antibody MTER1_HUMAN antibody MTERF domain containing 1 antibody mTERF domain containing protein 1 mitochondrial antibody mTERF domain-containing protein 1 antibody mTERF3 antibody Mterfd1 antibody Transcription termination factor 3, mitochondrial antibody |
| Product description | MTERFD1 belongs to the MTERF family which consists of four members including MTERF1, MTERF2, MTERF3 and MTERF4. Previous research showed that MTERFD1 is a mitochondrial protein that interacts with the mitochondrial DNA promoter region and decreases transcription initiation in mammalian mitochondria. This negative regulation is likely important for fine-tuning mitochondria transcription in response to physiological demands. Human mitochondrial transcription termination factor domain 1 (MTERFD1) was mutated in many types of cancer. In vivo and in vitro data indicated that MTERFD1 gene possesses oncogenic properties. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIHCICC |
| WB:1:1,000-1:2,000 IHC:1:50-1:200 ICC:1:50 | |
| Species Reactivity | HumanMouse |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | CGI 12 antibody mitochondrial antibody Mitochondrial transcription termination factor 3 antibody MTER1_HUMAN antibody MTERF domain containing 1 antibody mTERF domain containing protein 1 mitochondrial antibody mTERF domain-containing protein 1 antibody mTERF3 antibody Mterfd1 antibody Transcription termination factor 3 mitochondrial antibody |
|---|---|
| Molecular Weight(MW) | 48/38 kDa |
| Cellular Localization | Mitochondrion. |
Application
Fig1: Western blot analysis of MTERFD1 on different lysates using anti-MTERFD1 antibody at 1/1,000 dilution. Positive control： Lane1: Hela Lane2: Mouse kidney tissue Lane3: K562
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-MTERFD1 antibody. Counter stained with hematoxylin.| Positive Control | Hela, mouse kidney tissue lysate, K562, human liver tissue. |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 IHC:1:50-1:200 ICC:1:50 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
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