| 存储条件 |
|---|
| Product Name | AKR7A2 [C10-D5] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AFAR antibody AFAR1 antibody AFB1 aldehyde reductase 1 antibody AFB1 AR1 antibody AFB1-AR 1 antibody AFB1AR1 antibody Aflatoxin aldehyde reductase antibody Aflatoxin B1 aldehyde reductase member 2 antibody Aflatoxin beta1 aldehyde reductase antibody Aiar antibody AKR7 antibody Akr7a2 antibody Aldo keto reductase family 7 antibody Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase antibody Aldo keto reductase family 7 member A2 antibody Aldo keto reductase family 7, member A2 (aflatoxin aldehyde reductase) antibody Aldoketoreductase 7 antibody ARK72_HUMAN antibody SSA reductase antibody Succinic semialdehyde reductase antibody |
| Product description | Aflatoxin B1 aldehyde reductase member 2 is an enzyme that in humans is encoded by the AKR7A2 gene. It catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate and may have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). AKR7A2 has broad substrate specificity and NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). AKR7A2 can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro) and reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. It may be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. |
| Immunogen | peptide |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBICCIHC |
| WB:1:1,000-1:2,000 ICC:1:200 | |
| Species Reactivity | HumanZebra Fish |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | AFAR antibody AFAR1 antibody AFB1 aldehyde reductase 1 antibody AFB1 AR1 antibody AFB1-AR 1 antibody AFB1AR1 antibody Aflatoxin aldehyde reductase antibody Aflatoxin B1 aldehyde reductase member 2 antibody Aflatoxin beta1 aldehyde reductase antibody Aiar antibody AKR7 antibody Akr7a2 antibody Aldo keto reductase family 7 antibody Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase antibody Aldo keto reductase family 7 member A2 antibody Aldo keto reductase family 7 member A2 (aflatoxin aldehyde reductase) antibody Aldoketoreductase 7 antibody ARK72_HUMAN antibody SSA reductase antibody Succinic semialdehyde reductase antibody |
|---|---|
| Molecular Weight(MW) | 40 kDa |
| Cellular Localization | Cytoplasm, Golgi apparatus |
| SwissProt ID | O43488 |
|---|
Application
Fig1: Western blot analysis of AKR7A2 on human spermatozoa lysate using anti-AKR7A2 antibody at 1/1,000 dilution.
Application
Fig2: ICC staining AKR7A2 in HepG2 cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: Western blot analysis of AKR7A2 on hybrid fish (crucian-carp) liver tissue lysate using anti-AKR7A2 antibody at 1/1,000 dilution.| Positive Control | HepG2, human spermatozoa |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 ICC:1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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