Anti-DOK1抗体
参阅全部 DOK1 一抗
兔多克隆抗体to DOK1
Rabbit
适用于: WB, ICC/IFmore details
与反应: Human
Synthetic peptide corresponding to Human DOK1 aa 400-500.
Database link: Q99704
Jurkat whole cell lysate
Tyrosine kinase substrate p62DOK
Signals from most growth factors and cytokines are transduced by receptor tyrosine kinases or non-receptortyrosine kinases. Activated tyrosine kinases phosphorylatetheir substrates, which mediate the cellular response to extracellular stimuli. A long-sought major substrate termed p62dok (downstream of tyrosine kinase) for many tyrosine kinases including c-kit, v-abl, v-Fps, v-Src, v-Fms, and activated EGF, PDGF, IGF, VEGF and insulin receptors was identified recently from human and mouse by several laboratories. Upon phosphorylation, p62dok forms a complex with the ras GTPase-activating protein (RasGAP). p62dok represents a new family with very recently identified p56 dok.
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Liquid
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 7.2
Preservative: 0.02% Sodium azide
浓度
100 µg 浓度为 1 mg/ml
Immunogen affinity purified
Signals from most growth factors and cytokines are transduced by receptor tyrosine kinases or non-receptortyrosine kinases. Activated tyrosine kinases phosphorylatetheir substrates, which mediate the cellular response to extracellular stimuli. A long-sought major substrate termed p62dok (downstream of tyrosine kinase) for many tyrosine kinases including c-kit, v-abl, v-Fps, v-Src, v-Fms, and activated EGF, PDGF, IGF, VEGF and insulin receptors was identified recently from human and mouse by several laboratories. Upon phosphorylation, p62dok forms a complex with the ras GTPase-activating protein (RasGAP). p62dok represents a new family with very recently identified p56 dok.
多克隆
IgG
Abpromise™承诺保证使用ab8112于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 62 kDa. | |
| ICC/IF | Use a concentration of 2 µg/ml. |
Entrez Gene: 1796 Human
Omim: 602919 Human
SwissProt: Q99704 Human
Unigene: 103854 Human
DOK1 antibody
DOK1_HUMAN antibody
Downstream of tyrosine kinase 1 antibody
p62(dok) antibody
P62DOK antibody
pp62 antibody
Docking protein 1 62kD antibody
Docking protein 1 antibody
DOK 1 antibody
Western blot - Anti-DOK1 antibody (ab8112)
All lanes : Anti-DOK1 antibody (ab8112) at 1 µg/ml
Lane 1 : Jurkat cell lysates
Lane 2 : THP-1 cell lysate
Observed band size: 62 kDawhy is the actual band size different from the predicted?
Immunocytochemistry/ Immunofluorescence - Anti-DOK1 antibody (ab8112)
ab8112 at 2µg/ml staining DOK1 in K562 cells by ICC/IF
