Anti-Apolipoprotein B抗体
参阅全部 Apolipoprotein B 一抗
山羊多克隆抗体to Apolipoprotein B
Goat
Typically less than 1% cross reactivity against other types of apoLipoprotein was detected by ELISA against purified standards. This antibody reacts with human apoLipoprotein B and has negligible cross-reactivity with Type A-I, A-II, C-I, C-II, C-III, E and J apoLipoproteins. Specific cross reaction of anti-apoLipoprotein antibodies with antigens from other species has not been determined. Non-specific cross reaction of anti-apoLipoprotein antibodies with other human serum proteins is negligible.
适用于: WBmore details
与反应: Human
Full length native apoLipoprotein Type B (purified).
This antibody has been used to determine that atherosclerotic lesions in the human aorta contain considerable amounts of lipoproteins. These lipoproteins were observed to be complexed with components of the extracellular matrix (especially LDL and proteoglycans). The role of these matrix-lipoprotein complexes is not entirely clear, however, animal models of atherosclerosis have shown that increased cellular proliferation and increased production of extracellular matrix components occur following injury to the intimal layer of the aorta.
At least 9 distinct polymorphic forms of apolipoproteins are known. The apolipoproteins act as stabilizers of the intact lipoprotein particles. Quantitative measurements of HDL, LDL and VLDL particles in human serum are often used to estimate an individuals' relative risk of coronary heart disease. In addition, quantitative immunological measurements of certain apolipoproteins (especially A-1 and B) have been suggested to be more accurate estimators of coronary heart disease than measurements of lipoprotein particles (especially HDL and LDL). Abcam's apo-lipoproteins are derived from human plasma by density gradient ultracentrifugation and HPLC.
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Liquid
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Preservative: 0.01% Sodium azide
Constituents: 4.77% Sodium borate, 0.44% Sodium chloride, 0.15% EDTA
Immunogen affinity purified
This product has been prepared by immunoaffinity chromatography using immobilized antigens followed by extensive cross-adsorption against other apoLipoproteins and human serum proteins to remove any unwanted specificities.
At least 9 distinct polymorphic forms of apolipoproteins are known. The apolipoproteins act as stabilizers of the intact lipoprotein particles. Quantitative measurements of HDL, LDL and VLDL particles in human serum are often used to estimate an individuals' relative risk of coronary heart disease. In addition, quantitative immunological measurements of certain apolipoproteins (especially A-1 and B) have been suggested to be more accurate estimators of coronary heart disease than measurements of lipoprotein particles (especially HDL and LDL). Abcam's apo-lipoproteins are derived from human plasma by density gradient ultracentrifugation and HPLC.
多克隆
IgG
Abpromise™承诺保证使用ab7616于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | 1/200 - 1/1000. |
Entrez Gene: 338 Human
Omim: 107730 Human
SwissProt: P04114 Human
Unigene: 120759 Human
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ApoB 100 antibody
ApoB 48 antibody
APOB antibody
APOB_HUMAN antibody
Apolipoprotein B (including Ag(x) antigen) antibody
Apolipoprotein B 100 antibody
Apolipoprotein B 48 antibody
Apolipoprotein B antibody
Apolipoprotein B-48 antibody
Apolipoprotein B100 antibody
Apolipoprotein B48 antibody
FLDB antibody
LDLCQ4 antibody
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Apo B antibody
Apo B-100 antibody
Western blot - Anti-Apolipoprotein B antibody (ab7616)
Anti-Apolipoprotein B antibody (ab7616) at 1 µg/ml + Native Human Apolipoprotein B (ab77859) at 0.01 µg
Secondary
Rabbit polyclonal to Goat IgG - H&L - Pre-Adsorbed (HRP) (ab65486) at 1/3000 dilution
Developed using the ECL technique.
Exposure time: 3 minutes
