Anti-IL-1 alpha antibody

• 产品名称

  Anti-IL-1 alpha抗体
  参阅全部 IL-1 alpha 一抗

• 描述

  兔多克隆抗体to IL-1 alpha

• 宿主

  Rabbit

• 特异性

  In general, this antibody also detects primate IL-1a in the same formats using similar dilutions. The antiserum does not recognize human IL-1b or Mouse or Rabbit IL-1a. In ELISA formats and other immunoreactive assays, this antibody will recognize both the mature 17,000 MW IL-1a as well as the 31,000 MW IL-1a precursor in either non-denatured (native) or denatured samples. Unlike the IL-1b precursor, the native precursor of IL-1a is recognized by the antibody produced to the 17,000 MW form. The 31,000 precursor of IL-1a is biologically active and is found primarily intracellularly. The precursor of IL-1a, unlike that of IL-1b, is biologically active when applied to cells and is thought to have a role as a functional molecule intracellularly and can be found constitutively expressed in various cell. This antibody is also useful for neutralization of human and primate IL-1a activity in bioassays. It does not neutralize the biological activity IL-1b. It does not neutralize the biological activity of mouse, rat or rabbit IL-1a. It will neutralize primate IL-a. For neutralization, it is recommended to incubate the sample with a 1:100 dilution of the antibody for at least 4 hours before being tested. A control of similarly diluted normal rabbit IgG is recommended. This antibody can be used for FACS analysis. Caution should be exhibited as the F( c) domain of the rabbit IgG molecule may interact with cells non-specifically.

• 经测试应用

  适用于: ELISA, Neutralising, ICC/IF, IHC-P, Flow Cyt, WBmore details

• 种属反应性

  与反应: Mouse, Human
  预测可用于: Non human primates

• 免疫原

  Recombinant full length protein corresponding to Human IL-1 alpha.

• 常规说明

  
  

  The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

  If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

• 形式

  Liquid

• 存放说明

  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

• 存储溶液

  pH: 7.2
  Preservative: 0.01% Sodium azide
  Constituents: 0.424% Potassium phosphate solution, 0.88% Sodium chloride

• 纯化说明

  whole rabbit serum purified by DEAE fractionation

• 克隆

  多克隆

• 同种型

  IgG

The Abpromise guarantee

Abpromise™承诺保证使用ab7632于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

• 数据库链接

• Entrez Gene: 3552 Human

• Entrez Gene: 16175 Mouse

• Omim: 147760 Human

• SwissProt: P01583 Human

• SwissProt: P01582 Mouse

• Unigene: 1722 Human

• Unigene: 15534 Mouse

• 别名

• Hematopoietin-1 antibody

• IL 1 alpha antibody

• IL 1A antibody

• IL-1 alpha antibody

• Il-1a antibody

• IL1 ALPHA antibody

• IL1 antibody

• IL1A antibody

• IL1A_HUMAN antibody

• IL1F1 antibody

• Interleukin 1 alpha antibody

• Interleukin-1 alpha antibody

• Interleukin1 alpha antibody

• LAF antibody

• LEM antibody

• Preinterleukin 1 alpha antibody

• Pro interleukin 1 alpha antibody

• BAF antibody

• FAF antibody

• Hematopoietin 1 antibody