| 存储条件 |
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| Product Name | GLUT2 [JJ20-21] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | liver antibody Glucose Transporter 2 antibody Glucose Transporter GLUT2 antibody Glucose transporter type 2 antibody Glucose transporter type 2 liver antibody Glucose transporter, liver/islet antibody GLUT-2 antibody GLUT2 antibody GTR2_HUMAN antibody GTT2 antibody SLC2A2 antibody Solute carrier family 2 (facilitated glucose transporter) member 2 antibody Solute carrier family 2 facilitated glucose transporter member 2 antibody Solute carrier family 2, facilitated glucose transporter member 2 antibody |
| Product description | Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. Glut1, Glut3 and Glut4 are high-affinity transporters, whereas Glut2 is a low-affinity transporter. In adipose and muscle tissue, insulin stimulates a rapid and dramatic increase in glucose uptake, which is largely due to the redistribution of the insulin-inducible glucose transporter Glut4. In response to insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane and shows a much less dramatic translocation in response to insulin. Glut2 expression is seen in pancreatic beta cells, hepatocytes and basolateral membranes of intestinal and epithelial cells, while the highest expression of Glut3 has been found in neuronal tissue. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHCFC |
| WB:1:500-1:1,000 FC:1:50-1:100 IHC:1:50-1:200 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | liver antibody Glucose Transporter 2 antibody Glucose Transporter GLUT2 antibody Glucose transporter type 2 antibody Glucose transporter type 2 liver antibody Glucose transporter liver/islet antibody GLUT-2 antibody GLUT2 antibody GTR2_HUMAN antibody GTT2 antibody SLC2A2 antibody Solute carrier family 2 (facilitated glucose transporter) member 2 antibody Solute carrier family 2 facilitated glucose transporter member 2 antibody Solute carrier family 2 facilitated glucose transporter member 2 antibody |
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| Molecular Weight(MW) | 57 kDa |
| Cellular Localization | Membrane. |
| SwissProt ID | P11168 |
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Application
Fig1: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-GLUT2 antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human kideny tissue using anti-GLUT2 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-GLUT2 antibody. Counter stained with hematoxylin.
Application
Fig4: Flow cytometric analysis of HepG2 cells with GLUT2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody| Positive Control | MCF-7, Hela, HepG2, human liver tissue, human pancreas tissue, human kideny tissue. |
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| Application Notes | WB:1:500-1:1,000 FC:1:50-1:100 IHC:1:50-1:200 |
| Form | Liquid |
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| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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