| 存储条件 |
|---|
| Product Name | KDM5B |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Cancer/testis antigen 31 antibody CT31 antibody Histone demethylase JARID1B antibody JARID1B antibody Jumonji AT rich interactive domain 1B antibody Jumonji/ARID domain-containing protein 1B antibody Kdm5b antibody KDM5B_HUMAN antibody Lysine (K) specific demethylase 5B antibody Lysine demethylase 5B antibody Lysine specific demethylase 5B antibody Lysine-specific demethylase 5B antibody PLU-1 antibody PLU1 antibody PPP1R98 antibody Protein phosphatase 1 regulatory subunit 98 antibody PUT1 antibody putative DNA/chromatin binding motif antibody RBBP2H1A antibody RBP2 like antibody RBP2-H1 antibody Retinoblastoma-binding protein 2 homolog 1 antibody Retinoblastoma-binding protein 2 homolog 1A antibody |
| Product description | PLU-1 is a large (1,544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBFC |
| WB:1:500-1:1,000 FC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | Cancer/testis antigen 31 antibody CT31 antibody Histone demethylase JARID1B antibody JARID1B antibody Jumonji AT rich interactive domain 1B antibody Jumonji/ARID domain-containing protein 1B antibody Kdm5b antibody KDM5B_HUMAN antibody Lysine (K) specific demethylase 5B antibody Lysine demethylase 5B antibody Lysine specific demethylase 5B antibody Lysine-specific demethylase 5B antibody PLU-1 antibody PLU1 antibody PPP1R98 antibody Protein phosphatase 1 regulatory subunit 98 antibody PUT1 antibody putative DNA/chromatin binding motif antibody RBBP2H1A antibody RBP2 like antibody RBP2-H1 antibody Retinoblastoma-binding protein 2 homolog 1 antibody Retinoblastoma-binding protein 2 homolog 1A antibody |
|---|---|
| Molecular Weight(MW) | 176 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | Q9UGL1 |
|---|
Application
Fig1: Western blot analysis of KDM5B on?human KDM5B recombinant protein using anti-KDM5B antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of KDM5B on HEK293 (1) and KDM5B-hIgGFc transfected HEK293 (2) cell lysate using anti-KDM5B antibody at 1/1,000 dilution.
Application
Fig3: Flow cytometric analysis of MCF-7 cells with KDM5B antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human KDM5B recombinant protein, KDM5B-hIgGFc transfected HEK293 cell lysate, MCF-7. |
|---|---|
| Application Notes | WB:1:500-1:1,000 FC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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