| 存储条件 |
|---|
| Product Name | IL1RAPL1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IL 1 RAPL 1 antibody IL 1RAPL 1 antibody IL-1-RAPL-1 antibody IL-1RAPL-1 antibody IL1R8 antibody IL1RAPL 1 antibody IL1RAPL antibody IL1RAPL-1 antibody IL1RAPL1 antibody Interleukin 1 receptor 8 antibody Interleukin 1 receptor accessory protein like 1 antibody Interleukin-1 receptor accessory protein-like 1 antibody IRPL1_HUMAN antibody Mental retardation X linked 10 antibody Mental retardation X linked 21 antibody Mental retardation X linked 34 antibody MRX 21 antibody MRX 34 antibody MRX10 antibody MRX21 antibody MRX34 antibody Oligophrenin 4 antibody Oligophrenin-4 antibody Oligophrenin4 antibody OPHN 4 antibody OPHN4 antibody Three immunoglobulin domain containing IL 1 receptor related 2 antibody Three immunoglobulin domain-containing IL-1 receptor-related 2 antibody TIGIRR 2 antibody TIGIRR-2 antibody TIGIRR2 antibody X linked interleukin 1 receptor accessory protein like 1 antibody X-linked interleukin-1 receptor accessory protein-like 1 antibody |
| Product description | May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBICCFC |
| WB:1:500-1:2,000 ICC:1:50-1:200 FC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | IL 1 RAPL 1 antibody IL 1RAPL 1 antibody IL-1-RAPL-1 antibody IL-1RAPL-1 antibody IL1R8 antibody IL1RAPL 1 antibody IL1RAPL antibody IL1RAPL-1 antibody IL1RAPL1 antibody Interleukin 1 receptor 8 antibody Interleukin 1 receptor accessory protein like 1 antibody Interleukin-1 receptor accessory protein-like 1 antibody IRPL1_HUMAN antibody Mental retardation X linked 10 antibody Mental retardation X linked 21 antibody Mental retardation X linked 34 antibody MRX 21 antibody MRX 34 antibody MRX10 antibody MRX21 antibody MRX34 antibody Oligophrenin 4 antibody Oligophrenin-4 antibody Oligophrenin4 antibody OPHN 4 antibody OPHN4 antibody Three immunoglobulin domain containing IL 1 receptor related 2 antibody Three immunoglobulin domain-containing IL-1 receptor-related 2 antibody TIGIRR 2 antibody TIGIRR-2 antibody TIGIRR2 antibody X linked interleukin 1 receptor accessory protein like 1 antibody X-linked interleukin-1 receptor accessory protein-like 1 antibody |
|---|---|
| Molecular Weight(MW) | 80 kDa |
| Cellular Localization | Cell membrane. Cytoplasm. |
| SwissProt ID | Q9NZN1 |
|---|
Application
Fig1: Western blot analysis of IL1RAPL1 on ?human IL1RAPL1 recombinant protein using anti-IL1RAPL1 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of IL1RAPL1 on HEK293 (1) and IL1RAPL1-hIgGFc transfected HEK293 (2) cell lysate using anti-IL1RAPL1 antibody at 1/1,000 dilution.
Application
Fig3: Western blot analysis of IL1RAPL1 on different cell lysate using anti-IL1RAPL1 antibody at 1/1,000 dilution. Positive control： Lane1: A431 Lane2: SK-Hep-1 Lane3: HL-7702
Application
Fig4:ICC staining IL1RAPL1 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig5: Flow cytometric analysis of Hela cells with IL1RAPL1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human IL1RAPL1 recombinant protein, IL1RAPL1-hIgGFc transfected HEK293 cell lysate, A431, SK-Hep-1, HL-7702, Hela. |
|---|---|
| Application Notes | WB:1:500-1:2,000 ICC:1:50-1:200 FC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
抱歉，暂无相关文献
