| 存储条件 |
|---|
| Product Name | HDAC9 [C4-B7] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HD 7 antibody HD 7B antibody HD 9 antibody HD7 antibody HD7B antibody HD9 antibody HDAC 7 antibody HDAC 7B antibody HDAC 9 antibody HDAC 9B antibody HDAC 9FL antibody HDAC antibody HDAC7 antibody HDAC7B antibody HDAC9 antibody HDAC9_HUMAN antibody HDAC9B antibody HDAC9FL antibody HDRP antibody Histone deacetylase 4/5 related protein antibody Histone deacetylase 7 antibody Histone deacetylase 7B antibody Histone deacetylase 9 antibody Histone deacetylase 9A antibody Histone deacetylase related protein antibody Histone deacetylase-related protein antibody KIAA0744 antibody MEF2 interacting transcription repressor MITR antibody MEF2 interacting transcription repressor protein antibody MEF2-interacting transcription repressor MITR antibody MITR antibody |
| Product description | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription.Isoform 3 lacks active site residues and therefore is catalytically inactive. Represses MEF2-dependent transcription by recruiting HDAC1 and/or HDAC3. Seems to inhibit skeletal myogenesis and to be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBFC |
| WB:1:500-1:2,000 FC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | HD 7 antibody HD 7B antibody HD 9 antibody HD7 antibody HD7B antibody HD9 antibody HDAC 7 antibody HDAC 7B antibody HDAC 9 antibody HDAC 9B antibody HDAC 9FL antibody HDAC antibody HDAC7 antibody HDAC7B antibody HDAC9 antibody HDAC9_HUMAN antibody HDAC9B antibody HDAC9FL antibody HDRP antibody Histone deacetylase 4/5 related protein antibody Histone deacetylase 7 antibody Histone deacetylase 7B antibody Histone deacetylase 9 antibody Histone deacetylase 9A antibody Histone deacetylase related protein antibody Histone deacetylase-related protein antibody KIAA0744 antibody MEF2 interacting transcription repressor MITR antibody MEF2 interacting transcription repressor protein antibody MEF2-interacting transcription repressor MITR antibody MITR antibody |
|---|---|
| Molecular Weight(MW) | 111 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | Q9UKV0 |
|---|
Application
Fig1: Western blot analysis of HDAC9 on human HDAC9 recombinant protein using anti-HDAC9 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of HDAC9 on HEK293 (1) and HDAC9-hIgGFc transfected HEK293 (2) cell lysate using anti-HDAC9 antibody at 1/1,000 dilution.
Application
Fig3: Flow cytometric analysis of Hela cells with HDAC9 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human HDAC9 recombinant protein, HDAC9-hIgGFc transfected HEK293 cell lysate, Hela. |
|---|---|
| Application Notes | WB:1:500-1:2,000 FC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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