| 存储条件 |
|---|
| Product Name | ABCG1 [SU03-26] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ABC transporter 8 antibody ABC8 antibody ABCG1 antibody ABCG1_HUMAN antibody ATP-binding cassette sub family G member 1 antibody ATP-binding cassette sub-family G member 1 antibody ATP-binding cassette transporter 8 antibody ATP-binding cassette transporter member 1 of subfamily G antibody ATP-binding cassette, sub family G WHITE member 1 antibody homolog of Drosophila white antibody MGC34313 antibody White protein homolog antibody White protein homolog ATP binding cassette transporter 8 antibody WHITE1 antibody WHT1 antibody |
| Product description | ABCG1 (also designated ABC8 or human white gene), a member of the evolutionary conserved family of ATP-binding cassette (ABC) transporters, exhibits high homology with the Drosophila white gene. ABC transporters couple the energy of ATP hydrolysis to the translocation of various molecules across biological membranes. These proteins contain characteristic ATP-binding domains and transmembrane domains which form a channel-like structure for transport. ABCG1 functions to regulate cholesterol and phospholipid transport in macrophages. ABCG1 is highly expressed in several tissues, including brain, spleen, lung and placenta, and has been localized to the cell surface and intracellular compartments of cholesterol-laden macrophages. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBICC/IFIHC |
| WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 | |
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Alternative Names | ABC transporter 8 antibody ABC8 antibody ABCG1 antibody ABCG1_HUMAN antibody ATP-binding cassette sub family G member 1 antibody ATP-binding cassette sub-family G member 1 antibody ATP-binding cassette transporter 8 antibody ATP-binding cassette transporter member 1 of subfamily G antibody ATP-binding cassette sub family G WHITE member 1 antibody homolog of Drosophila white antibody MGC34313 antibody White protein homolog antibody White protein homolog ATP binding cassette transporter 8 antibody WHITE1 antibody WHT1 antibody |
|---|---|
| Molecular Weight(MW) | 110 kDa |
| Cellular Localization | Endoplasmic reticulum membrane, Golgi apparatus membrane. |
Application
Fig1: Western blot analysis of ABCG1 on THP-1 cell lysates using anti-ABCG1 antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-ABCG1 antibody. Counter stained with hematoxylin.| Positive Control | THP-1, human lung tissue. |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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