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| Product Name | PRDX2 [7F2] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Epididymis secretory sperm binding protein Li 2a antibody HEL S 2a antibody MGC4104 antibody Natural killer cell enhancing factor B antibody Natural killer cell-enhancing factor B antibody Natural Killer Enhancing Factor B antibody NKEF B antibody NKEF-B antibody NKEFB antibody Peroxiredoxin-2 antibody PRDX 2 antibody PRDX2 antibody PRDX2_HUMAN antibody PrP antibody PRX2 antibody PRXII antibody PTX1 antibody TDPX1 antibody Thiol Specific Antioxidant 1 antibody Thiol specific antioxidant protein antibody Thiol-specific antioxidant protein antibody Thioredoxin Dependent Peroxide Reductase 1 antibody Thioredoxin peroxidase 1 antibody Thioredoxin-dependent peroxide reductase 1 antibody Torin antibody TPX1 antibody TSA antibody |
| Product description | The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metal-catalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, although they are fairly promiscuous with regard to the hydroperoxide substrate. In addition to protection from ROS, peroxiredoxins are also involved in cell proliferation, differentiation and gene expression. PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization. The human PRX I gene encodes a protein that is expressed in several tissues, including liver, kidney, testis, lung and nervous system. PRX II is expressed in testis, while PRX III shows expression in lung. PRX I, II and III are overexpressed in breast cancer and may be involved in its development or progression. Upregulated protein levels of PRX I and II in Alzheimer's disease (AD) and Down syndrome (DS) indicate the involvement of PRX I and II in their pathogenesis. |
| Immunogen | Recombinant protein. |
| Clonality | Monoclonal |
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| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIHCFC |
| WB:1:2000-1:5000 IHC:1:50-1:200 FC:1:50-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | Epididymis secretory sperm binding protein Li 2a antibody HEL S 2a antibody MGC4104 antibody Natural killer cell enhancing factor B antibody Natural killer cell-enhancing factor B antibody Natural Killer Enhancing Factor B antibody NKEF B antibody NKEF-B antibody NKEFB antibody Peroxiredoxin-2 antibody PRDX 2 antibody PRDX2 antibody PRDX2_HUMAN antibody PrP antibody PRX2 antibody PRXII antibody PTX1 antibody TDPX1 antibody Thiol Specific Antioxidant 1 antibody Thiol specific antioxidant protein antibody Thiol-specific antioxidant protein antibody Thioredoxin Dependent Peroxide Reductase 1 antibody Thioredoxin peroxidase 1 antibody Thioredoxin-dependent peroxide reductase 1 antibody Torin antibody TPX1 antibody TSA antibody |
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| Molecular Weight(MW) | 22 kDa |
| Cellular Localization | Cytoplasm. |
| SwissProt ID | P32119 |
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Application
Fig1: Western blot analysis of Peroxiredoxin 2 on PC-3M (1) and MCF-7 (2) using anti-Peroxiredoxin 2 antibody at 1/2,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti- Peroxiredoxin 2 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human thyroid gland tissue using anti- Peroxiredoxin 2 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using anti- Peroxiredoxin 2 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti- Peroxiredoxin 2 antibody. Counter stained with hematoxylin.
Application
Fig6: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti- Peroxiredoxin 2 antibody. Counter stained with hematoxylin.
Application
Fig7: Flow cytometric analysis of Jurkat cells with Peroxiredoxin 2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-mouse IgG was used as the secondary antibody.| Positive Control | PC-3M, MCF-7, human liver cancer tissue, human thyroid gland tissue, human prostate cancer tissue, human kidney tissue, human placenta tissue. |
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| Application Notes | WB:1:2000-1:5000 IHC:1:50-1:200 FC:1:50-1:200 |
| Form | Liquid |
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| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
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