The antibody recognizes free N-terminus of mature HIV protease HIV1 and HIV2, but it does not react with the precursor.
Alternative Names
HIV1 HIV-I Human immunodeficiency virus type 1
Function
The HIV protease (PR) hydrolyzes polyproteins of HIV virus into functional protein products that are essential for its assembly and subsequent activity. This maturation process occurs as the virion buds from the host cell. HIV protease inhibitors are used in the treatment of patients with AIDS and were considered the first breakthrough in over a decade of AIDS research. HIV protease inhibitors can lower the viral load carried by AIDS patents.
Application
DB
Dot Blot analysis of recombinant HIV protease. The total amount of recombinant HIV-protease spotted on the nitrocellulose membrane are indicated in left column. Lane 1: anti-HIV protease, 0.2 ug/ml. Lane 2: anti-HIV protease, 1.0 ug/ml. Lane 3: anti-HIV protease, 2.0 ug/ml.
Additional Information
Form
Liquid
Storage Instructions
Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.
Storage Buffer
PBS, pH~7.4, State: Purified, State: Liquid purified IgG fraction (> 95% pure by SDS-PAGE), Preservative: 15mM Sodium Azide.
