| 存储条件 |
|---|
| Product Name | Omnimabs® 488 Rabbit anti-Mouse/Rat CD27 mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 24-182 of mouse CD27 (NP_001028298.1). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | FC |
| FC:5 μl per 10^6 cells in 100 μl volume | |
| Species Reactivity | MouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CD27 |
|---|---|
| Gene Synonyms | S152 S152. LPFS2 T14 TNFRSF7 Tp55 |
| Gene Full Name | CD27 molecule |
| Gene Summary | he protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008] |
| Alternative Names | S152 Tp55 Tnfrsf7 |
| Cellular Localization | Membrane, Single-pass type I membrane protein |
FC
1X10^6 A20 cells (negative control,left) and C57BL/6 mouse Splenocytes (right) were surface-stained with Omnimabs® 488 Rabbit anti-Mouse/Rat CD27 mAb (5μl/Test,orange line) or Omnimabs® 488 Rabbit IgG isotype control (5μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
FC
1X10^6 C57BL/6 mouse Splenocytes were surface-stained with Omnimabs® 488 Rabbit IgG isotype control (5μl/Test,left) or Omnimabs® 488 Rabbit anti-Mouse/Rat CD27 mAb (5μl/Test,right).| Application Notes | FC:5 μl per 10^6 cells in 100 μl volume |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 2-8℃. Avoid freeze. |
| Storage Buffer | PBS with 0.03% proclin300, 0.2% BSA, pH7.3. |
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