| 存储条件 |
|---|
| Product Name | TREM2 Rabbit pAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant fusion protein containing a sequence of human TREM2 (NP_061838.1). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCWB |
| WB:1:500-1:1000 IHC:1:50-1:100 ICC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TREM2 |
|---|---|
| Gene Synonyms | AD17 PLOSL2 TREM-2 Trem2a Trem2b Trem2c |
| Gene Full Name | triggering receptor expressed on myeloid cells 2 |
| Gene Summary | This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012] |
| Molecular Weight(MW) | 25kDa(Observed MW: 2535-50kDa) |
| Cellular Localization | Cell membrane,Secreted. |
WB
Western blot analysis of TREM2 in various cell lines lysates using TREM2 antibody.
IHC
Immunohistochemistry analysis of paraffin-embedded mouse spleen using TREM2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
ICC/IF
Immunofluorescent analysis of NIH3T3 cells using TREM2 antibody at dilution of 1:100 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L).| Application Notes | WB:1:500-1:1000 IHC:1:50-1:100 ICC:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
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