| 存储条件 |
|---|
| Product Name | Smad2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Drosophila, homolog of, MADR2 antibody hMAD-2 antibody HsMAD2 antibody JV18 antibody JV18-1 antibody JV181 antibody MAD antibody MAD homolog 2 antibody MAD Related Protein 2 antibody Mad-related protein 2 antibody MADH2 antibody MADR2 antibody MGC22139 antibody MGC34440 antibody Mother against DPP homolog 2 antibody Mothers against decapentaplegic homolog 2 antibody Mothers against decapentaplegic, Drosophila, homolog of, 2 antibody Mothers against DPP homolog 2 antibody OTTHUMP00000163489 antibody Sma and Mad related protein 2 antibody Sma- and Mad-related protein 2 MAD antibody SMAD 2 antibody SMAD family member 2 antibody SMAD, mothers against DPP homolog 2 antibody SMAD2 antibody SMAD2_HUMAN antibody |
| Product description | Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of TGF∫/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGF∫ and Activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to Activin/TGF∫ signaling by interfering with TGF∫-mediated phosphorylation of other Smad proteins. |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICCIHC |
| ICC:1:50-1:100 IHC:1:50-1:200: | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | Drosophila homolog of MADR2 antibody hMAD-2 antibody HsMAD2 antibody JV18 antibody JV18-1 antibody JV181 antibody MAD antibody MAD homolog 2 antibody MAD Related Protein 2 antibody Mad-related protein 2 antibody MADH2 antibody MADR2 antibody MGC22139 antibody MGC34440 antibody Mother against DPP homolog 2 antibody Mothers against decapentaplegic homolog 2 antibody Mothers against decapentaplegic Drosophila homolog of 2 antibody Mothers against DPP homolog 2 antibody OTTHUMP00000163489 antibody Sma and Mad related protein 2 antibody Sma- and Mad-related protein 2 MAD antibody SMAD 2 antibody SMAD family member 2 antibody SMAD mothers against DPP homolog 2 antibody SMAD2 antibody SMAD2_HUMAN antibody |
|---|---|
| Cellular Localization | Cytoplasm, Nucleus |
| SwissProt ID | Q15796 |
|---|
Application
Fig1： Immunocytochemical staining of SW480 cells using anti-Smad2 rabbit polyclonal antibody.
Application
Fig2： Immunocytochemical staining of SK-BR-3 cells using anti-Smad2 rabbit polyclonal antibody.
Application
Fig3： Immunocytochemical staining of HepG2 cells using anti-Smad2 rabbit polyclonal antibody.
Application
Fig4： Immunohistochemical analysis of paraffin- embedded human liver cancer tissue using anti-Smad2 rabbit polyclonal antibody.
Application
Fig5： Immunohistochemical analysis of paraffin- embedded mouse skeletal muscle tissue using anti-Smad2 rabbit polyclonal antibody.
Application
Fig6： Immunohistochemical analysis of paraffin- embedded mouse placenta tissue using anti-Smad2 rabbit polyclonal antibody.
Application
Fig7： Immunohistochemical analysis of paraffin- embedded mouse heart tissue using anti-Smad2 rabbit polyclonal antibody.| Positive Control | SW480, SK-BR-3, HepG2, mouse placenta tissue, human liver cancer tissue, mouse heart tissue, mouse skeletal muscle tissue |
|---|---|
| Application Notes | ICC:1:50-1:100 IHC:1:50-1:200: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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