| 存储条件 |
|---|
| Product Name | Bcl-x |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Apoptosis regulator Bcl X antibody Bcl 2 like 1 antibody Bcl 2 like 1 protein antibody Bcl xL antibody BCL XL/S antibody Bcl xS antibody Bcl2 like1 antibody BCL2-related gene antibody BCL2-related protein, long isoform, included; BCLXL, included antibody BCL2-related protein, short isoform, included; BCLXS, included antibody BCL2L antibody BCL2L1 antibody Bclx antibody DKFZp781P2092 antibody MGC113803 antibody MGC99998 antibody |
| Product description | Bcl-x, a member of the Bcl-2 protein family, inhibits cell death, or apoptosis (1). Bcl-x is expressed as two isomeric forms, Bcl-xL and Bcl-xS, and is typically present in the cytosol in association with the mitochondrial membrane. Bcl-xL forms heterodimers with various proteins, including Bax, Bak and Bcl-2 (2). It has been found that heterodimerization with Bax does not seem to be required for anti-apoptotic activity (3). Since Bcl-xL can form an ion channel in synthetic lipid membranes, there is a strong possibility that this property plays a role in heterodimerization-independent cell survival (4). The Bcl-X(S) isoform promotes apoptosis. |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHCFCIP |
| WB:1:500-1,000 ICC:1:100 IHC:1:50-100 IP:1:10 FC:1:50 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | Apoptosis regulator Bcl X antibody Bcl 2 like 1 antibody Bcl 2 like 1 protein antibody Bcl xL antibody BCL XL/S antibody Bcl xS antibody Bcl2 like1 antibody BCL2-related gene antibody BCL2-related protein long isoform included BCLXL included antibody BCL2-related protein short isoform included BCLXS included antibody BCL2L antibody BCL2L1 antibody Bclx antibody DKFZp781P2092 antibody MGC113803 antibody MGC99998 antibody |
|---|---|
| Molecular Weight(MW) | 26 (Bcl-xL) / 19 (Bcl-xS) |
| Cellular Localization | Cytoplasm, Nucleus membrane, Cytoplasmic vesicle Mitochondrion matrix, Mitochondrion outer/ inner membrane |
| SwissProt ID | Q07817 |
|---|
Application
Fig1: Western blot analysis of K562 cell lysate using anti-Bcl-x.
Application
Fig2： Immunohistochemical analysis of human paraffin-embedded prostate carcinoma tissue using anti-Bcl-x.| Positive Control | K562, human paraffin-embedded prostate carcinoma tissue. |
|---|---|
| Application Notes | WB:1:500-1,000 ICC:1:100 IHC:1:50-100 IP:1:10 FC:1:50 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 ℃. Stable for 12 months from date of receipt |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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