| 存储条件 |
|---|
| Product Name | CD5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD 5 antibody CD5 antibody CD5 antigen (p56 62) antibody CD5 antigen antibody CD5 molecule antibody CD5_HUMAN antibody LEU1 antibody LyA antibody Lymphocyte antigen T1/Leu-1 antibody OTTHUMP00000236973 antibody T-cell surface glycoprotein CD5 antibody T1 antibody |
| Product description | CD5 (Lymphocyte antigen T1/Leu-1) is a transmembrane glycoprotein which has been implicated as a receptor in the regulation of T-cell proliferation (1). CD5 is part of the scavenger receptor cysteine-rich (SRCR) family group B and it is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by T cell leukemia, lymphomas, and activated T cells. Occasionally, CD5 antigen is also expressed on a subset of B cells. Mantle cell lymphomas (same as diffuse centrocytic lymphomas) are CD5+ while the follicle center cell lymphomas are CD5. A ligand for CD72/LYB-2, CD5 has been linked to negative regulation of T cell and B cell receptors signaling (2) |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHCIP |
| WB:1:1,000 ICC:1:100-250 IHC:1:250-500 IP:1:50 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CD 5 antibody CD5 antibody CD5 antigen (p56 62) antibody CD5 antigen antibody CD5 molecule antibody CD5_HUMAN antibody LEU1 antibody LyA antibody Lymphocyte antigen T1/Leu-1 antibody OTTHUMP00000236973 antibody T-cell surface glycoprotein CD5 antibody T1 antibody |
|---|---|
| Molecular Weight(MW) | 67kDa |
| Cellular Localization | Cell membrane |
| SwissProt ID | P06127 |
|---|
Application
Fig1: Western blot analysis using anti-CD5 on cells that were either (A) untreated or (B) treated with TPA.
Application
Fig2： Immunohistochemical analysis of paraffin-embedded human tonsils using anti-CD5.| Positive Control | TPA |
|---|---|
| Application Notes | WB:1:1,000 ICC:1:100-250 IHC:1:250-500 IP:1:50 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 ℃. Stable for 12 months from date of receipt |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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