Anti-NFkB p105 / p50 antibody

• 产品名称

  Anti-NFkB p105 / p50抗体
  参阅全部 NFkB p105 / p50 一抗

• 描述

  兔多克隆抗体to NFkB p105 / p50

• 宿主

  Rabbit

• 特异性

  Recognition is at the N-terminus. This antibody will "supershift " NFkB complexes containing the human p50 subunit. Control peptide ab7550 will compete only with the specific reaction of antiserum with Human NFkB p50 (NFKB1).

• 经测试应用

  适用于: ELISA, GSA, WB, IHC-Pmore details

• 种属反应性

  与反应: Human
  

• 免疫原

  Synthetic peptide corresponding to Human NFkB p105/ p50 aa 1-100 (N terminal) conjugated to keyhole limpet haemocyanin. Synthetic peptide:

  AEDDPYLGRFEQMF

  conjugated to KLH, corresponding to N terminal amino acids 2-15 of Human NFkB p50.
  Database link: P19838

  Run BLAST with Run BLAST with 

• 常规说明

  NFkB is formed as a homo- or hetero-dimer. Subunits include p50 (NFkB1), p65 (RelA), c-Rel, RelB and p52 (NFkB2). The classic NFkB form exists as a p50-p65 heterodimer and predominates in many cell types. Many of the possible combinatorial forms of homo- and heterodimers have been identified and growing evidence indicates that different forms of NFkB have different functions in cells. Nuclear translocation of NFkB is confirmed by the use of electrophorectic mobility shift assays or by immunoblotting with nuclear extracts. The subunit composition of NFkB is confirmed by the use of antibodies that "supershift" the DNA/protein complex.

  
  

  The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

  If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

• 形式

  Liquid

• 存放说明

  Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• 存储溶液

  Preservative: 0.01% Sodium azide
  Constituent: Whole serum

• 纯度

  Whole antiserum

• 纯化说明

  This product was prepared from monospecific antiserum by delipidation and defibrination.

• 克隆

  多克隆

• 同种型

  IgG

The Abpromise guarantee

Abpromise™承诺保证使用ab7549于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

• 数据库链接

• Entrez Gene: 4790 Human

• Omim: 164011 Human

• SwissProt: P19838 Human

• Unigene: 618430 Human

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