Anti-GNAT1抗体
参阅全部 GNAT1 一抗
兔多克隆抗体to GNAT1
Rabbit
Detects Rod Transducin alpha from bovine outer rod segments and sheep retinal extract.
适用于: WBmore details
与反应: Sheep
预测可用于: Rat, Dog, Human, Xenopus laevis
Synthetic peptide corresponding to Human GNAT1 aa 1-100.
WB: sheep retinal extracts
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Liquid
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 99% PBS
浓度
100 µg 浓度为 1 mg/ml
Immunogen affinity purified
Vision involves the conversion of light into electrochemical signals that are processed by the retina and subsequently sent to and interpreted by the brain. The process of converting light into an electrochemical signal begins when the membrane-bound protein, rhodopsin, absorbs light within the retina. Photoexcitation of rhodopsin causes the cytoplasmic surface of the protein to become catalytically active. In the active state, rhodopsin activates transducin, a GTP binding protein. Once activated, transducin promotes the hydrolysis of cGMP by phosphodiesterase (PDE). The decrease of intracellular cGMP concentration causes the ion channels within the outer segment of the rod or cone to close, thus causing membrane hyperpolarization and, eventually, signal transmission. Rhodopsin activity is believed to be shut off by phosphorylation followed by binding of the soluble protein, arrestin. Transducin, once activated by rhodopsin, promotes the hydrolysis of cGMP by PDE. The subunit composition of transducin differs between different photoreceptor cells. Rod transducin consists of rod transducin alpha (Tr alpha), T beta, and T gamma. Cone transducin is composed of cone transducin alpha (Tc alpha), T beta and T gamma. Differential transducin subunit composition of transducin is believed to be responsible for the different light sensitivities between photoreceptive cells.
多克隆
IgG
Abpromise™承诺保证使用ab3504于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 40 kDa). |
Entrez Gene: 2779 Human
Entrez Gene: 399262 Xenopus laevis
Omim: 139330 Human
SwissProt: P11488 Human
SwissProt: P38407 Xenopus laevis
Unigene: 517978 Human
CSNBAD3 antibody
GBT1 antibody
GNAT1 antibody
GNAT1_HUMAN antibody
GNATR antibody
guanine nucleotide binding protein (G protein) alpha transducing activity polypeptide 1 antibody
guanine nucleotide binding protein G(T) alpha 1 subunit antibody
Guanine nucleotide-binding protein G(t) subunit alpha-1 antibody
Rod specific transducin antibody
rod-type transducin alpha subunit antibody
Transducin alpha-1 chain antibody
transducin, rod-specific antibody
Western blot - Anti-GNAT1 antibody (ab3504)
Western blot detection of Trabsducin alpha on sheep retinal extracts using ab3504.
