| 存储条件 |
|---|
| Product Name | Angiotensin Converting Enzyme 2 [SN0754] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ACE 2 antibody ACE related carboxypeptidase antibody ACE-related carboxypeptidase antibody ACE2 antibody ACE2_HUMAN antibody ACEH antibody Angiotensin converting enzyme 2 antibody Angiotensin converting enzyme homolog antibody Angiotensin converting enzyme like protein antibody Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2 antibody Angiotensin I converting enzyme 2 antibody Angiotensin-converting enzyme homolog antibody DKFZP434A014 antibody EC 3.4.17 antibody metalloprotease MPROT 15 antibody Metalloprotease MPROT15 antibody OTTHUMP00000022963 antibody Processed angiotensin-converting enzyme 2 antibody |
| Product description | Angiotensin-converting enzyme (ACE) is a carboxyl-terminal dipeptidyl exopeptidase that converts angiotensin I to the potent vasopressive hormone, angiotensin II. There are two isoforms of ACE, the pulmonary ACEP and the testicular ACET. ACEP is a glycoprotein expressed in vascular endothelial cells of the lung, liver, adrenal cortex, pancreas, kidney and spleen. The ACET isoform is expressed exclusively in adult testis by developing sperm cells, specifically late pachytene spermatocytes. Additionally, ACE inactivates bradykinin, a vasodepressor peptide, and is involved in blood pressure regulation and fluid/electrolyte homeostasis. ACE2 is the first known human homolog of ACE. Unlike ACE, which is expressed ubiquitously throughout the vasculature, ACE2 is expressed only in cardiac, renal and testicular cells. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBICCIHCIP |
| WB:1:1,000-1:5,000 ICC:1:100-1:500 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | ACE 2 antibody ACE related carboxypeptidase antibody ACE-related carboxypeptidase antibody ACE2 antibody ACE2_HUMAN antibody ACEH antibody Angiotensin converting enzyme 2 antibody Angiotensin converting enzyme homolog antibody Angiotensin converting enzyme like protein antibody Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2 antibody Angiotensin I converting enzyme 2 antibody Angiotensin-converting enzyme homolog antibody DKFZP434A014 antibody EC 3.4.17 antibody metalloprotease MPROT 15 antibody Metalloprotease MPROT15 antibody OTTHUMP00000022963 antibody Processed angiotensin-converting enzyme 2 antibody |
|---|---|
| Molecular Weight(MW) | 92 kDa |
| Cellular Localization | Secreted, Cell membrane, Cytoplasm. |
Application
Fig1: Western blot analysis of ACE2 on human kidney lysates using anti-ACE2 antibody at 1/1,000 dilution.
Application
Fig2: ICC staining ACE2 in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: ICC staining ACE2 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: ICC staining ACE2 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-ACE2 antibody. Counter stained with hematoxylin.
Application
Fig6: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-ACE2 antibody. Counter stained with hematoxylin.
Application
Fig7: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-ACE2 antibody. Counter stained with hematoxylin.| Positive Control | 293, MCF-7, HepG2, human breast carcinoma tissue, human kidney tissue, mouse kidney tissue. |
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| Application Notes | WB:1:1,000-1:5,000 ICC:1:100-1:500 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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