| 存储条件 |
|---|
| Product Name | TTR [C5-E10] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Amyloid polyneuropathy antibody Amyloidosis I antibody ATTR antibody Carpal tunnel syndrome 1 antibody CTS antibody CTS1 antibody Dysprealbuminemic euthyroidal hyperthyroxinemia antibody Dystransthyretinemic hyperthyroxinemia antibody Epididymis luminal protein 111 antibody HEL111 antibody HsT2651 antibody PALB antibody Prealbumin amyloidosis type I antibody Prealbumin antibody Prealbumin Thyroxine-binding antibody Senile systemic amyloidosis antibody TBPA antibody Thyroxine binding prealbumin antibody Transthyretin antibody TTHY_HUMAN antibody TTR antibody TTR protein antibody |
| Product description | Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermed-iate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein). The gene encoding Prealbumin maps to human chromosome 18q12.1. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBICCIHCFC |
| WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | Amyloid polyneuropathy antibody Amyloidosis I antibody ATTR antibody Carpal tunnel syndrome 1 antibody CTS antibody CTS1 antibody Dysprealbuminemic euthyroidal hyperthyroxinemia antibody Dystransthyretinemic hyperthyroxinemia antibody Epididymis luminal protein 111 antibody HEL111 antibody HsT2651 antibody PALB antibody Prealbumin amyloidosis type I antibody Prealbumin antibody Prealbumin Thyroxine-binding antibody Senile systemic amyloidosis antibody TBPA antibody Thyroxine binding prealbumin antibody Transthyretin antibody TTHY_HUMAN antibody TTR antibody TTR protein antibody |
|---|---|
| Molecular Weight(MW) | 16 kDa |
| Cellular Localization | Secreted. Cytoplasm |
| SwissProt ID | P02766 |
|---|
Application
Fig1: Western blot analysis of Prealbumin on human Prealbumin recombinant protein using anti- Prealbumin antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of Prealbumin on HEK293 (1) and Prealbumin -hIgGFc transfected HEK293 (2) cell lysate using anti- Prealbumin antibody at 1/1,000 dilution.
Application
Fig3: ICC staining Prealbumin (green) and Actin filaments (red) in A549 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: ICC staining Prealbumin (green) and Actin filaments (red) in MCF-7 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti- Prealbumin antibody. Counter stained with hematoxylin.
Application
Fig6: Flow cytometric analysis of A549 cells with Prealbumin antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human Prealbumin recombinant protein, Prealbumin -hIgGFc transfected HEK293 cell lysate, A549, MCF-7, human liver cancer tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
抱歉，暂无相关文献
