| 存储条件 |
|---|
| Product Name | CD21 [SC0681] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C3DR antibody CD 21 antibody CD21 antibody Complement C3d receptor antibody Complement component (3d/Epstein Barr virus) receptor 2 antibody Complement receptor type 2 antibody CR antibody Cr2 antibody CR2_HUMAN antibody CVID7 antibody EBV receptor antibody EBV-R antibody Epstein Barr virus receptor antibody Epstein-Barr virus receptor antibody EVBR antibody SLEB9 antibody |
| Product description | CD21 is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B cells, follicular dendritic cells, pharyngeal and cervical epithelial cells and a subset of thymocytes. The adaptive immune response is tightly regulated to limit responding cells in an antigen-specific manner. On B cells, co-receptors CD21/CD19 modulate the strength of B cell Ag receptor (BCR) signals, thereby influencing cell fate. Complement receptor (CR) type 2 (CR2/ CD21) is normally expressed during the immature and mature stages of B cell development. In association with CD19, CR21 plays an important role in enhancing mature B cell responses to foreign antigens. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBICCIHCIPFC |
| WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | C3DR antibody CD 21 antibody CD21 antibody Complement C3d receptor antibody Complement component (3d/Epstein Barr virus) receptor 2 antibody Complement receptor type 2 antibody CR antibody Cr2 antibody CR2_HUMAN antibody CVID7 antibody EBV receptor antibody EBV-R antibody Epstein Barr virus receptor antibody Epstein-Barr virus receptor antibody EVBR antibody SLEB9 antibody |
|---|---|
| Molecular Weight(MW) | 130-155 kDa |
| Cellular Localization | Membrane. |
Application
Fig1: Western blot analysis of CD21 on different lysates using anti-CD21 antibody at 1/1,000 dilution. Positive control: Lane 1: Daudi Lane 2: Raji
Application
Fig2: ICC staining CD21 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: ICC staining CD21 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD21 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD21 antibody. Counter stained with hematoxylin.
Application
Fig6: Immunohistochemical analysis of paraffin-embedded human gastric cancer tissue using anti-CD21 antibody. Counter stained with hematoxylin.| Positive Control | Daudi, Raji, A549, HepG2, human tonsil tissue, human gastric cancer tissue, human spleen tissue. |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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