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MMP2 [B11-E6]

MMP2 [B11-E6]

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基础信息
存储条件
产品详情
Product Profile
Product NameMMP2 [B11-E6]
Antibody TypePrimary Antibodies
Antigen Alias72 kDa gelatinase antibody 72kD type IV collagenase antibody CLG 4 antibody CLG 4A antibody CLG4 antibody CLG4A antibody Collagenase Type 4 alpha antibody Collagenase type IV A antibody Gelatinase A antibody Gelatinase alpha antibody Gelatinase neutrophil antibody Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase antibody Matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) antibody Matrix Metalloproteinase 2 antibody Matrix metalloproteinase II antibody Matrix metalloproteinase-2 antibody MMP 2 antibody MMP II antibody MMP-2 antibody MMP2 antibody MMP2_HUMAN antibody MONA antibody Neutrophil gelatinase antibody PEX antibody TBE 1 antibody TBE-1 antibody
Product descriptionThe matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV, V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.
ImmunogenRecombinant protein
Key Feature
ClonalityMonoclonal
IsotypeIgG1
Host SpeciesMouse
Tested ApplicationsWBFC

WB:1:500-1:2,000
FC:1:100-1:200
Species ReactivityHumanMouse
Concentration2mg/ml
Target Information
Alternative Names72 kDa gelatinase antibody 72kD type IV collagenase antibody CLG 4 antibody CLG 4A antibody CLG4 antibody CLG4A antibody Collagenase Type 4 alpha antibody Collagenase type IV A antibody Gelatinase A antibody Gelatinase alpha antibody Gelatinase neutrophil antibody Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase antibody Matrix metalloproteinase 2 (gelatinase A
72kDa gelatinase
72kDa type IV collagenase) antibody Matrix Metalloproteinase 2 antibody Matrix metalloproteinase II antibody Matrix metalloproteinase-2 antibody MMP 2 antibody MMP II antibody MMP-2 antibody MMP2 antibody MMP2_HUMAN antibody MONA antibody Neutrophil gelatinase antibody PEX antibody TBE 1 antibody TBE-1 antibody
Molecular Weight(MW)72 kDa
Cellular LocalizationSecreted. Membrane. Nucleus
Database Links
SwissProt IDP08253P33434
Application

Application

Fig1: Western blot analysis of MMP2 on human MMP2 recombinant protein using anti-MMP2 antibody at 1/1,000 dilution.

Application

Fig2: Western blot analysis of MMP2 on HEK293 (1) and MMP2-hIgGFc transfected HEK293 (2) cell lysate using anti-MMP2 antibody at 1/1,000 dilution.

Application

Fig3: Western blot analysis of MMP2 on different cell lysate using anti-MMP2 antibody at 1/1,000 dilution. Positive control: Lane1: MCF-7 Lane2: Raw264.7 Lane3: HUVEC Lane4: T47D

Application

Fig4:Flow cytometric analysis of Hela cells with MMP-2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
Positive ControlHuman MMP2 recombinant protein, MMP2-hIgGFc transfected HEK293, MCF-7, Raw264.7, HUVEC, T47D, Hela.
Application NotesWB:1:500-1:2,000
FC:1:100-1:200
Additional Information
FormLiquid
Storage InstructionsStore at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.


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