| 存储条件 |
|---|
| Product Name | IFNAR1 [A5-A3] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Alpha type antiviral protein antibody Antiviral protein, alpha-type antibody Antiviral protein, beta-type antibody AVP antibody Beta type antiviral protein antibody CRF2-1 antibody Cytokine receptor class-II member 1 antibody Cytokine receptor family 2 member 1 antibody IFN alpha REC antibody IFN alpha receptor antibody IFN alpha/beta Receptor alpha antibody IFN beta receptor antibody IFN Interferon-beta receptor antibody IFN-alpha/beta receptor 1 antibody IFN-R-1 antibody IFNAR antibody Ifnar1 antibody IFNBR antibody IFRC antibody INAR1_HUMAN antibody Interferon (alpha beta and omega) receptor 1 antibody interferon alpha and beta receptor subunit 1 antibody Interferon alpha/beta receptor 1 antibody Interferon alpha/beta receptor alpha chain antibody Interferon beta receptor 1 antibody interferon receptor 1 antibody Interferon-alpha receptor antibody Type I interferon receptor 1 antibody |
| Product description | Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIHCICC |
| WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouse |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | Alpha type antiviral protein antibody Antiviral protein alpha-type antibody Antiviral protein beta-type antibody AVP antibody Beta type antiviral protein antibody CRF2-1 antibody Cytokine receptor class-II member 1 antibody Cytokine receptor family 2 member 1 antibody IFN alpha REC antibody IFN alpha receptor antibody IFN alpha/beta Receptor alpha antibody IFN beta receptor antibody IFN Interferon-beta receptor antibody IFN-alpha/beta receptor 1 antibody IFN-R-1 antibody IFNAR antibody Ifnar1 antibody IFNBR antibody IFRC antibody INAR1_HUMAN antibody Interferon (alpha beta and omega) receptor 1 antibody interferon alpha and beta receptor subunit 1 antibody Interferon alpha/beta receptor 1 antibody Interferon alpha/beta receptor alpha chain antibody Interferon beta receptor 1 antibody interferon receptor 1 antibody Interferon-alpha receptor antibody Type I interferon receptor 1 antibody |
|---|---|
| Molecular Weight(MW) | 56 kDa |
| Cellular Localization | Endosome. Cell membrane. |
Application
Fig1: Western blot analysis of IFNAR1 on different lysates using anti- IFNAR1 antibody at 1/500 dilution. Positive control: Lane 1: K562 Lane 1: A431 Lane 1: Siha Lane 1: Mouse brain tissue
Application
Fig2: ICC staining IFNAR1(red) in NCCIT cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: ICC staining IFNAR1(green) in SHG-44 cells. Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human lung tissue using anti- IFNAR1 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human colon tissue using anti- IFNAR1 antibody. Counter stained with hematoxylin.
Application
Fig6: Immunohistochemical analysis of paraffin-embedded human skin tissue using anti- IFNAR1 antibody. Counter stained with hematoxylin.| Positive Control | K562, A431, Siha, mouse brain tissue lysate, NCCIT, SHUG-44, human lung tissue, human skin tissue, human colon tissue. |
|---|---|
| Application Notes | WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
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