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Cathepsin B [J11-A11]

Cathepsin B [J11-A11]

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包装规格 交货周期 质量标准 目录价 会员专享价 数量
50ul 现货2-3天 原装正品
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基础信息
存储条件
产品详情
Product Profile
Product NameCathepsin B [J11-A11]
Antibody TypePrimary Antibodies
Antigen AliasAmyloid precursor protein secretase antibody APP secretase antibody APPS antibody CATB_HUMAN antibody Cathepsin B heavy chain antibody Cathepsin B1 antibody CathepsinB antibody CPSB antibody CTSB antibody cysteine protease antibody OTTHUMP00000116009 antibody OTTHUMP00000229510 antibody OTTHUMP00000229511 antibody OTTHUMP00000229512 antibody OTTHUMP00000229514 antibody OTTHUMP00000229515 antibody OTTHUMP00000229516 antibody Preprocathepsin B antibody
Product descriptionCathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. In humans, it is coded by the CTSB gene. A wide array of diseases results in elevated levels of cathepsin B, which causes numerous pathological processes including cell death, inflammation, and production of toxic peptides. Focusing on neurological diseases, cathepsin B gene knockout studies in an epileptic rodent model have shown cathepsin B causes a significant amount of the apoptotic cell death that occurs as a result of inducing epilepsy. Mutations in the CTSB gene have been linked to tropical pancreatitis, a form of chronic pancreatitis
Immunogenrecombinant protein
Key Feature
ClonalityMonoclonal
IsotypeIgG1
Host SpeciesMouse
Tested ApplicationsWBICCIHC

WB:1:5,000-1:10,000
ICC:1:200-1:500
Species ReactivityHumanZebra Fish
Concentration2mg/ml
Target Information
Alternative NamesAmyloid precursor protein secretase antibody APP secretase antibody APPS antibody CATB_HUMAN antibody Cathepsin B heavy chain antibody Cathepsin B1 antibody CathepsinB antibody CPSB antibody CTSB antibody cysteine protease antibody OTTHUMP00000116009 antibody OTTHUMP00000229510 antibody OTTHUMP00000229511 antibody OTTHUMP00000229512 antibody OTTHUMP00000229514 antibody OTTHUMP00000229515 antibody OTTHUMP00000229516 antibody Preprocathepsin B antibody
Molecular Weight(MW)38 kDa
Cellular LocalizationLysosome, secreted
Database Links
SwissProt IDP07858
Application

Application

Fig1: Western blot analysis of Cathepsin B on SW480 cell lysate using anti-Cathepsin B antibody at 1/5,000 dilution.

Application

Fig2: ICC staining Cathepsin B in HepG2 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Application

Fig3: ICC staining Cathepsin B (red) in HepG2 cells.  Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Positive ControlSW480, HepG2
Application NotesWB:1:5,000-1:10,000
ICC:1:200-1:500
Additional Information
FormLiquid
Storage InstructionsStore at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.


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