| 存储条件 |
|---|
| Product Name | TRAF6 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | E3 ubiquitin-protein ligase TRAF6 antibody Interleukin 1 signal transducer antibody Interleukin-1 signal transducer antibody MGC 3310 antibody MGC:3310 antibody MGC3310 antibody OTTHUMP00000232772 antibody OTTHUMP00000232773 antibody RING finger protein 85 antibody RNF 85 antibody RNF85 antibody TNF receptor associated factor 6 antibody TNF receptor-associated factor 6 antibody TNF receptor-associated factor 6, E3 ubiquitin protein ligase antibody TRAF 6 antibody Traf6 antibody TRAF6_HUMAN antibody |
| Product description | TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/TRANCE/RANKL and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICCIHC |
| WB:1:500-1:1,000 ICC:1:100-1:200 | |
| Species Reactivity | HumanMouseRatFish |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | E3 ubiquitin-protein ligase TRAF6 antibody Interleukin 1 signal transducer antibody Interleukin-1 signal transducer antibody MGC 3310 antibody MGC:3310 antibody MGC3310 antibody OTTHUMP00000232772 antibody OTTHUMP00000232773 antibody RING finger protein 85 antibody RNF 85 antibody RNF85 antibody TNF receptor associated factor 6 antibody TNF receptor-associated factor 6 antibody TNF receptor-associated factor 6 E3 ubiquitin protein ligase antibody TRAF 6 antibody Traf6 antibody TRAF6_HUMAN antibody |
|---|---|
| Molecular Weight(MW) | 60 kDa |
| Cellular Localization | Cytoplasm, nucleus |
| SwissProt ID | Q9Y4K3 |
|---|
Application
Fig1: Western blot analysis on cell lysates using anti-TRAF6 rabbit polyclonal antibodies.
Application
Fig2: ICC staining TRAF6 in Hela cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: Western blot analysis of TRAF6 on hybrid fish (crucian-carp) heart tissue lysate using anti-TRAF6 antibody at 1/500 dilution.| Positive Control | Hela, MCF-7, F9, PC12, hybrid fish (crucian-carp) heart tissue lysate. |
|---|---|
| Application Notes | WB:1:500-1:1,000 ICC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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