| 存储条件 |
|---|
| Product Name | Angiopoietin 1 (ANGPT1) Goat Polyclonal Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Peptide with sequence C-PDFSSQKLQH, from the internal region of the protein sequence according to NP_001137.2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Goat |
| Tested Applications | WB |
| WB:1-2ug/ml | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ANGPT1 |
|---|---|
| Gene Synonyms | AGP1 AGPT ANG1 HAE5 AGPT-1 |
| Gene Full Name | angiopoietin 1 |
| Gene Summary | This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Mutations in this gene are associated with hereditary angioedema. [provided by RefSeq, Aug 2020] |
| Molecular Weight(MW) | 50kDa |
| Cellular Localization | Secreted. |
WB
HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human ANGPT1 with DDK (FLAG) tag probed with ANGPT1 antibody (1ug/ml) in Lane A and probed with anti-DDK Tag (1:1000,in Lane C. Mock-transfected HEK293 probed with ANGPT1 antibody (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence..| Application Notes | WB:1-2ug/ml |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C as received. |
| Storage Buffer | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
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