| 存储条件 |
|---|
| Product Name | PTP epsilon (PTPRE) Mouse Monoclonal Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Full length human recombinant protein of human PTPRE (NP_006495) produced in HEK293T cell. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHCWB |
| WB:1:2000 IHC:1:50 ICC:1:100 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 0.7mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PTPRE |
|---|---|
| Gene Synonyms | PTPE HPTPE R-PTP-EPSILON |
| Gene Full Name | protein tyrosine phosphatase receptor type E |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq, Oct 2015] |
| Alternative Names | HPTPE PTPE R-PTP-EPSILON |
| Molecular Weight(MW) | 80kDa |
| Source | Store at -20°C as received.Stable for 12 months from date of receipt. |
| Cellular Localization | Cell membrane,Cytoplasm. |
WB
Western blot analysis of extracts (10ug) from 3 different cell lines by using anti-PTPRE monoclonal antibody at 1:200 dilution.
IHC
Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-PTPRE mouse monoclonal antibody. (heat-induced epitope retrieval by 1mM EDTA in 10mM Tris, pH8.5, 120°C for 3min)
ICC/IF
Immunofluorescent staining of HT29 cells using anti-PTPRE mouse monoclonal antibody.| Application Notes | WB:1:2000 IHC:1:50 ICC:1:100 |
|---|
| Form | Liquid |
|---|---|
| Storage Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
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