| 存储条件 |
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| Product Name | PI3-kinase p110 subunit alpha |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta antibody 5-bisphosphate 3-kinase catalytic subunit delta isoform antibody APDS antibody GRB1 antibody IMD14 antibody p110d antibody p110delta antibody p110dp85a antibody p85-ALPHA antibody Phosphatidylinositol 3 kinase catalytic delta polypeptide antibody Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta isoform antibody Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit delta antibody Phosphatidylinositol 4,5 bisphosphate 3 kinase, catalytic subunit delta antibody Phosphatidylinositol 45 bisphosphate 3 kinase catalytic subunit delta isoform antibody Phosphatidylinositol-4 antibody Phosphoinositide 3 kinase B antibody Phosphoinositide 3 kinase C antibody Phosphoinositide 3 kinase catalytic delta polypeptide antibody Phosphoinositide 3 kinase, catalytic, delta polypeptide variant p37delta antibody PI3 kinase p110 subunit delta antibody PI3-kinase subunit delta antibody PI3K antibody PI3K-delta antibody PI3Kdelta antibody Pik3cd antibody PIK3R1 antibody PK3CD antibody PK3CD_HUMAN antibody PtdIns 3 kinase p110 antibody PtdIns 3 kinase subunit p110 delta antibody PtdIns-3-kinase subunit delta antibody PtdIns-3-kinase subunit p110-delta antibody |
| Product description | Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains.Various p110 isoforms have been identified. p110α and p110β interact with p85α, and p110α has also been shown to interact with p85β in vitro. p110δ expression is restricted to white blood cells. It has been shown to bind p85α and β, but it apparently does not phosphorylate these subunits. p110δ seems to have the capacity to autophosphorylate. p110γ does not interact with the p85 subunits. It has been shown to be activated by α and βγ heterotrimeric G proteins. |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIF |
| WB:1:1,000 IP:1-2 μg per 100-500 μg of total protein IF:1:50-500 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta antibody 5-bisphosphate 3-kinase catalytic subunit delta isoform antibody APDS antibody GRB1 antibody IMD14 antibody p110d antibody p110delta antibody p110dp85a antibody p85-ALPHA antibody Phosphatidylinositol 3 kinase catalytic delta polypeptide antibody Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta isoform antibody Phosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit delta antibody Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta antibody Phosphatidylinositol 45 bisphosphate 3 kinase catalytic subunit delta isoform antibody Phosphatidylinositol-4 antibody Phosphoinositide 3 kinase B antibody Phosphoinositide 3 kinase C antibody Phosphoinositide 3 kinase catalytic delta polypeptide antibody Phosphoinositide 3 kinase catalytic delta polypeptide variant p37delta antibody PI3 kinase p110 subunit delta antibody PI3-kinase subunit delta antibody PI3K antibody PI3K-delta antibody PI3Kdelta antibody Pik3cd antibody PIK3R1 antibody PK3CD antibody PK3CD_HUMAN antibody PtdIns 3 kinase p110 antibody PtdIns 3 kinase subunit p110 delta antibody PtdIns-3-kinase subunit delta antibody PtdIns-3-kinase subunit p110-delta antibody |
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| Molecular Weight(MW) | 110kDa |
| Cellular Localization | Cytoplasm, membrane |
| SwissProt ID | P42336 |
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Application
Fig1: Western blot analysis of PI 3-kinase p110α expression in Jurkat whole cell lysate.
Application
Fig2： Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic and membrane localization.| Positive Control | Hela, Jurkat. |
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| Application Notes | WB:1:1,000 IP:1-2 μg per 100-500 μg of total protein IF:1:50-500 |
| Form | Liquid |
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| Storage Instructions | Store at +4℃ |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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