| 存储条件 |
|---|
| Product Name | PAX5 [6A1] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | B cell lineage specific activator antibody B cell lineage specific activator protein antibody B cell specific activator protein antibody B cell specific transcription factor antibody B-cell-specific transcription factor antibody BSAP antibody EBB-1 antibody KLP antibody Paired box 5 antibody Paired box gene 5 (B cell lineage specific activator protein) antibody Paired box gene 5 (B cell lineage specific activator) antibody Paired box gene 5 antibody Paired box homeotic gene 5 antibody Paired box protein Pax 5 antibody Paired box protein Pax-5 antibody Paired domain gene 5 antibody PAX 5 antibody PAX5 antibody PAX5_HUMAN antibody Transcription factor PAX 5 antibody |
| Product description | The human paired box protein Pax-5 (PAX5) is a member of the paired box domain family of transcription factors that play a role in B-cell differentiation, neural development, and spermatogenesis (1). As a result, its expression is detected in the developing central nervous system (CNS) and testis (1). In particular, PAX5 is essential for maintaining the identity and function of mature B cells during late B lymphopoiesis (2). PAX5 is a B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation (3). During B-cell differentiation, PAX5 interacts with DAXX, a bridge protein that helps PAX5 to function as both a transcriptional activator and a repressor (4). A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia (1). |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHCFC |
| WB:1:1,000 ICC:1:100 IHC:1:100 FC:1:10-100 | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | B cell lineage specific activator antibody B cell lineage specific activator protein antibody B cell specific activator protein antibody B cell specific transcription factor antibody B-cell-specific transcription factor antibody BSAP antibody EBB-1 antibody KLP antibody Paired box 5 antibody Paired box gene 5 (B cell lineage specific activator protein) antibody Paired box gene 5 (B cell lineage specific activator) antibody Paired box gene 5 antibody Paired box homeotic gene 5 antibody Paired box protein Pax 5 antibody Paired box protein Pax-5 antibody Paired domain gene 5 antibody PAX 5 antibody PAX5 antibody PAX5_HUMAN antibody Transcription factor PAX 5 antibody |
|---|---|
| Molecular Weight(MW) | 45kDa |
| Cellular Localization | Nucleus |
| SwissProt ID | Q02548 |
|---|
Application
Fig1: Western blot analysis on (A) Ramos, (B) human tonsil, and (C) Daudi lysates using anti-PAX5.
Application
Fig2： Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PAX5.| Positive Control | Ramos, human tonsil tissue. |
|---|---|
| Application Notes | WB:1:1,000 ICC:1:100 IHC:1:100 FC:1:10-100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 ℃. Stable for 12 months from date of receipt |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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