| 存储条件 |
|---|
| Product Name | Estrogen Receptor alpha |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DKFZp686N23123 antibody ER alpha antibody ER antibody ER-alpha antibody Era antibody ESR antibody ESR1 antibody ESR1_HUMAN antibody ESRA antibody Estradiol receptor antibody Estrogen nuclear receptor alpha antibody Estrogen receptor 1 antibody Estrogen receptor alpha 3*,4,5,6,7*/822 isoform antibody Estrogen receptor alpha antibody Estrogen receptor alpha delta 3*,4,5,6,7*,8*/941 isoform antibody Estrogen receptor alpha delta 3*,4,5,6,7*/819 2 isoform antibody Estrogen receptor alpha delta 4 +49 isoform antibody Estrogen receptor alpha delta 4*,5,6,7*/654 isoform antibody Estrogen receptor alpha delta 4*,5,6,7,8*/901 isoform antibody Estrogen receptor alpha E1 E2 1 2 antibody Estrogen receptor alpha E1 N2 E2 1 2 antibody Estrogen receptor antibody ESTRR antibody NR3A1 antibody Nuclear receptor subfamily 3 group A member 1 antibody |
| Product description | Estrogen receptor alpha (ER alpha) is a nuclear protein and member of the steroid hormone receptor family. ER alpha possesses both DNA binding and ligand binding domains, and exerts a significant role in activating the transcription of certain genes (1). Ligand-dependent dimerization and phosphorylation both function to regulate the transcriptional activation of ER alpha (2). The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy (3). |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1000 IHC:1:500-1000 | |
| Species Reactivity | HumanBaboon |
| Concentration | 1mg/ml |
| Alternative Names | DKFZp686N23123 antibody ER alpha antibody ER antibody ER-alpha antibody Era antibody ESR antibody ESR1 antibody ESR1_HUMAN antibody ESRA antibody Estradiol receptor antibody Estrogen nuclear receptor alpha antibody Estrogen receptor 1 antibody Estrogen receptor alpha 3* 4 5 6 7*/822 isoform antibody Estrogen receptor alpha antibody Estrogen receptor alpha delta 3* 4 5 6 7* 8*/941 isoform antibody Estrogen receptor alpha delta 3* 4 5 6 7*/819 2 isoform antibody Estrogen receptor alpha delta 4 +49 isoform antibody Estrogen receptor alpha delta 4* 5 6 7*/654 isoform antibody Estrogen receptor alpha delta 4* 5 6 7 8*/901 isoform antibody Estrogen receptor alpha E1 E2 1 2 antibody Estrogen receptor alpha E1 N2 E2 1 2 antibody Estrogen receptor antibody ESTRR antibody NR3A1 antibody Nuclear receptor subfamily 3 group A member 1 antibody |
|---|---|
| Molecular Weight(MW) | 66 kDa |
| Cellular Localization | Cytoplasm, Nucleus, Cell membrane Golgi apparatus |
| SwissProt ID | P03372 |
|---|
Application
Fig1: Western blot analysis on MCF-7 cell lysate using anti-ER-alpha.
Application
Fig2： Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-ER-alpha.| Application Notes | WB:1:500-1000 IHC:1:500-1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 ℃. Stable for 12 months from date of receipt |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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