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Anti-ALK-1 antibody

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  • 产品名称

    Anti-ALK-1抗体
    参阅全部 ALK-1 一抗

  • 描述

    山羊多克隆抗体to ALK-1

  • 宿主

    Goat

  • 经测试应用

    适用于: WBmore details

  • 种属反应性

    与反应: Human

  • 免疫原

    Synthetic peptide within Human ALK-1 aa 450 to the C-terminus (Cysteine residue). The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.

    Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

  • 阳性对照

    • Lung and liver extracts.

  • 常规说明

    Activin A receptor, type II-like 1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. ACVRL1 is most highly expressed in human placenta and lung. ACVRL1 deficiency causes hemorrhagic telangiectasia type 2 (HHT2; MIM 600376 ) also known as Rendu-Osler-Weber syndrome 2 (ORW2). Note: ACVRL1 is also known as ALK1 - not to be confused with the similarly named ALK (anaplastic lymphoma kinase).


    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

  • 形式

    Liquid

  • 存放说明

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

  • 存储溶液

    pH: 7.3
    Preservative: 0.02% Sodium azide
    Constituents: Tris buffered saline, 0.5% BSA

  • 浓度

    • 100 µg 浓度为 0.5 mg/ml

  • 纯度

    Immunogen affinity purified

  • 纯化说明

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

  • Primary antibody说明

    Activin A receptor, type II-like 1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. ACVRL1 is most highly expressed in human placenta and lung. ACVRL1 deficiency causes hemorrhagic telangiectasia type 2 (HHT2; MIM 600376 ) also known as Rendu-Osler-Weber syndrome 2 (ORW2). Note: ACVRL1 is also known as ALK1 - not to be confused with the similarly named ALK (anaplastic lymphoma kinase).

  • 克隆

    多克隆

  • 同种型

    IgG

The Abpromise guarantee

Abpromise™承诺保证使用ab10179于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。

应用Ab评论说明
WB

Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 56 kDa). 

1 hour primary incubation is recommended for this product.

  • 数据库链接

  • 别名

    • Activin receptor like kinase 1 antibody

    • Activin receptor-like kinase 1 antibody

    • ACVL1_HUMAN antibody

    • ACVRL1 antibody

    • ACVRLK1 antibody

    • ALK-1 antibody

    • ALK1 antibody

    • HHT antibody

    • HHT2 antibody

    • ORW2 antibody

    • Osler Rendu Weber syndrome 2 antibody

    • Serine/threonine protein kinase receptor R3 antibody

    • Serine/threonine-protein kinase receptor R3 antibody

    • SKR3 antibody

    • TGF B superfamily receptor type I antibody

    • TGF-B superfamily receptor type I antibody

    • TSR-I antibody

    • TSR1 antibody

    • Activin A receptor antibody

    • Activin A receptor type II like 1 antibody

    • Activin A receptor, type II like kinase 1 antibody

Western blot - Anti-ALK-1 antibody (ab10179)

Western blot - Anti-ALK-1 antibody (ab10179)

Anti-ALK-1 antibody (ab10179) at 2 µg/ml + MCF7 lysate at 35 µg

Developed using the ECL technique.

Predicted band size: 56 kDa
Observed band size: 60 kDa
why is the actual band size different from the predicted?