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Anti-MYRIP antibody

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100ug
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产品详情
  • 产品名称

    Anti-MYRIP抗体

  • 描述

    山羊多克隆抗体to MYRIP

  • 宿主

    Goat

  • 经测试应用

    适用于: WBmore details

  • 种属反应性

    与反应: Human

  • 免疫原

    Synthetic peptide: KDLMEPALESAVMY, corresponding to C terminal amino acids 846-859 of Human MYRIP.

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • 常规说明


    A molecular complex composed of Rab27A, MYRIP and myosin VIIa bridges retinal melanosomes to the actin cytoskeleton and thereby mediates the local trafficking of these organelles. The defect of this molecular complex is likely to account for the perinuclear mislocalization of the melanosomes observed in the retinal pigment epithelium cells of myosin VIIa-defective mice.


    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

  • 形式

    Liquid

  • 存放说明

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

  • 存储溶液

    pH: 7.3
    Preservative: 0.02% Sodium azide
    Constituents: Tris buffered saline, 0.5% BSA

  • 浓度

    • 100 µg 浓度为 0.5 mg/ml

  • 纯度

    Immunogen affinity purified

  • 纯化说明

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

  • Primary antibody说明

    A molecular complex composed of Rab27A, MYRIP and myosin VIIa bridges retinal melanosomes to the actin cytoskeleton and thereby mediates the local trafficking of these organelles. The defect of this molecular complex is likely to account for the perinuclear mislocalization of the melanosomes observed in the retinal pigment epithelium cells of myosin VIIa-defective mice.

  • 克隆

    多克隆

  • 同种型

    IgG


  • The Abpromise guarantee

  • Abpromise™承诺保证使用ab10149于以下的经测试应用

  • “应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。

  • 应用Ab评论说明
    WB(1)

    Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 96 kDa. 

    1 hour primary incubation is recommended for this product.

  • 数据库链接

  • 别名

    • Exophilin-8 antibody

    • Exophilin8 antibody

    • FLJ44025 antibody

    • MGC130034 antibody

    • MGC130035 antibody

    • Myosin VIIA and Rab interacting protein antibody

    • Myosin-VIIa- and Rab-interacting protein antibody

    • Myrip antibody

    • MYRIP_HUMAN antibody

    • Rab effector MyRIP antibody

    • SLAC 2C antibody

    • SLAC2 C antibody

    • SlaC2-c antibody

    • SLAC2C antibody

    • Slp homolog lacking C2 domains c antibody

    • Slp homologue lacking C2 domains antibody

    • Slp homologue lacking C2 domains c antibody

    • Synaptotagmin like protein homologue lacking C2 domains c antibody

    • synaptotagmin-like protein lacking C2 domains C antibody

    • DKFZp586F1018 antibody

    • Exophilin 8 antibody

    • Exophilin antibody

    • Western blot - Anti-MYRIP antibody (ab10149)

      Western blot - Anti-MYRIP antibody (ab10149)

      Anti-MYRIP antibody (ab10149) at 0.3 µg/ml + Human Amygdala lysates at 35 µg

      Developed using the ECL technique.

      Predicted band size: 96 kDa