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Anti-SIRT4 antibody

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  • 产品名称

    Anti-SIRT4抗体
    参阅全部 SIRT4 一抗

  • The Abpromise guarantee

  • Abpromise™承诺保证使用ab10140于以下的经测试应用

  • “应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。

  • 应用Ab评论说明
    WB

    Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 36 kDa). 

    1 hour primary incubation is recommended for this product.

    IHC-P

    Use a concentration of 2 - 3 µg/ml. Steamed antigen retrieval with citrate buffer pH 6 is recommended.

  • 数据库链接

  • Entrez Gene: 519328 Cow

  • Entrez Gene: 23409 Human

  • Entrez Gene: 75387 Mouse

  • Entrez Gene: 100125349 Pig

  • Entrez Gene: 304539 Rat

  • Omim: 604482 Human

  • SwissProt: Q1JQC6 Cow

  • SwissProt: Q9Y6E7 Human

  • SwissProt: Q8R216 Mouse

  • Unigene: 50861 Human

  • Unigene: 332616 Mouse

  • 描述

    山羊多克隆抗体to SIRT4

  • 宿主

    Goat

  • 经测试应用

    适用于: WBIHC-Pmore details

  • 种属反应性

    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog, Pig

  • 免疫原

    Synthetic peptide:

    SRCGELLPLIDPC

    , corresponding to C terminal amino acids 302-314 of Human SIRT4.

    Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

  • 阳性对照

    • IHC: Human skeletal muscle and pancreas tissue WB: Human kidney and U937 lysate, HEK293 cell lysate

  • 常规说明


    This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.


    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

  • 形式

    Liquid

  • 存放说明

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

  • 存储溶液

    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: Tris buffered saline, 0.5% BSA

  • 浓度


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    批次浓度查询

    • 100 µg 浓度为 0.5 mg/ml

    • 纯度

      Immunogen affinity purified

    • 纯化说明

      Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

    • Primary antibody说明

      This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

    • 克隆

      多克隆

    • 同种型

      IgG

    • 别名

    • MGC130046 antibody

    • MGC130047 antibody

    • MGC57437 antibody

    • NAD dependent deacetylase sirtuin 4 antibody

    • NAD dependent protein deacetylase sirtuin 4 antibody

    • NAD-dependent ADP-ribosyltransferase sirtuin-4 antibody

    • NAD-dependent protein deacetylase sirtuin-4 antibody

    • NAD-dependent protein lipoamidase sirtuin-4, mitochondrial antibody

    • Regulatory protein SIR2 homolog 4 antibody

    • Silent mating type information regulation 2 homolog antibody

    • Sir 2 like 4 antibody

    • SIR 2 like protein 4 antibody

    • Sir2 like 4 antibody

    • SIR2 like protein 4 antibody

    • SIR2-like protein 4 antibody

    • SIR2L 4 antibody

    • SIR2L4 antibody

    • SIR4_HUMAN antibody

    • SIRT 4 antibody

    • Sirt4 antibody

    • Sirtuin (silent mating type information regulation 2 homolog) 4 antibody

    • Sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae) antibody

    • Sirtuin 4 antibody

    • Sirtuin type 4 antibody

    • Sirtuin-4 antibody

    • Sirtuin4 antibody

    数据库链接