CDC 37 antibody Cdc37 antibody CDC37 cell division cycle 37 homolog antibody CDC37 cell division cycle 37 S cerevisiae homolog antibody CDC37 cell division cycle 37, S cerevisiae, homolog of antibody Cdc37 homolog antibody CDC37 protein antibody CDC37_HUMAN antibody CDC37A antibody cell division cycle 37 antibody Cell division cycle 37 homolog antibody Hsp90 chaperone protein kinase targeting subunit antibody Hsp90 chaperone protein kinase targeting subunit p50Cdc37 antibody Hsp90 chaperone protein kinase-targeting subunit antibody Hsp90 co chaperone Cdc37 antibody Hsp90 co-chaperone Cdc37 antibody p50 antibody p50Cdc37 antibody S cerevisiae hypothetical protein CDC37 antibody
Product description
Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc25A, Cdc25B and Cdc25C protein tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory tyrosine residues. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with Hsp90. Cdc34, Cdc27 and Cdc16 function as ubiquitin-conjugating enzymes. Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (anaphase-promoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation.
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser13 of human CDC37.
Modification
p-S13
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Recombinant rabbit
Tested Applications
WBIP
WB:1:1,000-1:2,000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
CDC 37 antibody Cdc37 antibody CDC37 cell division cycle 37 homolog antibody CDC37 cell division cycle 37 S cerevisiae homolog antibody CDC37 cell division cycle 37 S cerevisiae homolog of antibody Cdc37 homolog antibody CDC37 protein antibody CDC37_HUMAN antibody CDC37A antibody cell division cycle 37 antibody Cell division cycle 37 homolog antibody Hsp90 chaperone protein kinase targeting subunit antibody Hsp90 chaperone protein kinase targeting subunit p50Cdc37 antibody Hsp90 chaperone protein kinase-targeting subunit antibody Hsp90 co chaperone Cdc37 antibody Hsp90 co-chaperone Cdc37 antibody p50 antibody p50Cdc37 antibody S cerevisiae hypothetical protein CDC37 antibody
Fig1: Western blot analysis of Phospho-CDC37(S13) on different lysates using anti-Phospho-CDC37(S13) antibody at 1/1,000 dilution. Positive control: Lane 1: NIH/3T3 Lane 2: Jurkat
Positive Control
NIH/3T3, Jurkat.
Application Notes
WB:1:1,000-1:2,000
Additional Information
Form
Liquid
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
