CK 9 antibody CK-9 antibody Cytokeratin 9 antibody Cytokeratin-9 antibody Cytokeratin9 antibody EPPK antibody K1C9_HUMAN antibody K9 antibody Keratin 9 antibody Keratin antibody Keratin type I cytoskeletal 9 antibody Keratin-9 antibody Keratin9 antibody KRT 9 antibody Krt9 antibody Spermatid Perinuclear Ring Manchette Protein K9 antibody type I cytoskeletal 9 antibody
Product description
Cytokeratins comprise a diverse group of intermediate filament proteins that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratin 9 is an unusually large, type I acidic cytokeratin that differentiates human plantar and palmar epidermal cells. Cytokeratin 9 localizes to the suprabasal layers as well as the upper epidermal layers such as the glandular ridges and interridges. The domains of cytokeratin 9 include a head, an α-helical coiled-coil-forming rod, and a tail; cytokeratin 9 shares significant homology with cytokeratin 10. Mutations in the cytokeratin 9 gene correlate with the development of epidermolytic palmoplantar keratoderma (EPPK), an autosomal dominant inherited skin disorder that is characterized by hyperkeratosis of the skin over the palms and soles.
Immunogen
recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Recombinant rabbit
Tested Applications
WBIHCIP
WB:1:500-1:1,000 IHC:1:50-1:200
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
CK 9 antibody CK-9 antibody Cytokeratin 9 antibody Cytokeratin-9 antibody Cytokeratin9 antibody EPPK antibody K1C9_HUMAN antibody K9 antibody Keratin 9 antibody Keratin antibody Keratin type I cytoskeletal 9 antibody Keratin-9 antibody Keratin9 antibody KRT 9 antibody Krt9 antibody Spermatid Perinuclear Ring Manchette Protein K9 antibody type I cytoskeletal 9 antibody
