GTP binding protein RAB10 antibody Rab10 antibody RAB10 member RAS oncogene family antibody RAB10_HUMAN antibody Ras related GTP binding protein antibody Ras related GTP binding protein RAB10 antibody Ras-related protein Rab-10 antibody
Product description
The Ras-related superfamily of guanine nucleotide binding proteins, which includes the Ral / Rec, Rap, R-Ras, and Rho / Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles. Several members of the Rab subfamily have been identified, each of which is found at a particular stage of a membrane transport pathway.
Immunogen
Recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Host Species
Mouse
Tested Applications
WBICC
WB:1:500-1:1,000 ICC:1:50-1:200
Species Reactivity
HumanMouse
Concentration
2mg/ml
Purification
Unpurified
Target Information
Alternative Names
GTP binding protein RAB10 antibody Rab10 antibody RAB10 member RAS oncogene family antibody RAB10_HUMAN antibody Ras related GTP binding protein antibody Ras related GTP binding protein RAB10 antibody Ras-related protein Rab-10 antibody
Fig1: Western blot analysis of Rab10 on Hela (1) and NIH/3T3 (2) cell lysate using anti-Rab10 antibody at 1/1,000 dilution.
Application
Fig2: ICC staining Rab10 (green) in LOVO cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Positive Control
Hela, NIH-3T3, LOVO.Hela, NIH-3T3, LOVO.
Application Notes
WB:1:500-1:1,000 ICC:1:50-1:200
Additional Information
Form
Liquid
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
